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0NUDC_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionNuclear migration protein nudc (nuclear distribution protein c homolog).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The function of the CS domain is unknown. The CS domain is sometimes found C-terminal to the CHORD domain () in metazoan proteins.ut occurs separately from the CHORD domain in plants. This association is thought to be indicative of an functional interaction between CS and CHORD domains .
Hsp20 is a mammalian small heat-shock protein family that occurs most abundantly in skeletal muscle and heart. It has a tendency to form dimers.ia a disulphide linkage formed by an N-terminal cysteine.ow heat stability and a poor chaperoning ability in comparison with other family members. Structurally.his and related proteins contain a beta-sandwich fold consisting of 8 strands in 2 beta-sheets in a greek-key topology .The SSF signature in this entry is currently under review. Please be aware that some of the protein hits may be false positives.
  IPR008978:HSP20-like chaperone
SequencesProtein: NUDC_HUMAN (331 aa)
mRNA: CR612818 NM_006600
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 66 residues, 27120810-27121007Exon2: 28 residues, 27123166-27123244Exon3: 70 residues, 27140534-27140738Exon4: 24 residues, 27140830-27140896Exon5: 41 residues, 27141737-27141854Exon6: 67 residues, 27141948-27142143Exon7: 30 residues, 27144467-27144551Exon8: 41 residues, 27144645-27144764Exon9: 91 residues, 27145207-27145474Exon10: 2 residues, -Jump to NUDC_HUMANExon1: 63 residues, 27120819-27121007Exon2: 28 residues, 27123166-27123244Exon3: 59 residues, 27133326-27133497Exon4: 70 residues, 27140534-27140738Exon5: 24 residues, 27140830-27140896Exon6: 41 residues, 27141737-27141854Exon7: 67 residues, 27141948-27142143Exon8: 30 residues, 27144467-27144551Exon9: 41 residues, 27144645-27144764Exon10: 71 residues, 27145207-27145416Exon11: 2 residues, -Jump to NUDC_HUMAN  
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Loci Cluster (Details)Loci: 2494 27120810-27145474 ~-25K 818(NUDC)(+)Loci: 2495 27192784-27199731 ~-7K 822(+)Loci: 2496 27541099-27553008 ~-12K 833(SYTL1)(+)Loci: 3786 27604712-27689256 ~-85K 852(WASF2)(-)Loci: 2497 27972369-28023401 ~-51K 864(STX12)(+)Loci: 3787 28173405-28287718 ~-114K 879(EYA3)(-)Loci: 2493 27062219-27063534 ~-1K 814(SFN)(+)Link out to UCSC