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0ZNT4_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameSLC30A4
DescriptionZinc transporter 4 (znt-4) (solute carrier family 30 member 4).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005385 zinc ion transporter activity (TAS)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Members of this family are integral membrane proteins.hatare found to increase tolerance to divalent metal ions suchas cadmium.inc.nd cobalt. These proteins are considered tobe efflux pumps that remove these ions from cells however others are implicated in ion uptake . The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts.ften containing low-complexity sequence.
  IPR002524:Cation efflux protein
IPR002524:Cation_efflux 
Evalue:-91.8860549926758 
Location:114-417
SequencesProtein: ZNT4_HUMAN (429 aa)
mRNA: NM_013309
Local Annotation
Synapse Ontology
endosome of the presynaptic compartment. A cellular structure that is involved in the transport of proteins in the neuron after the proteins are endocytosed from the outside to the inside of the cell.
sdb:0088 endosome  (Evidence:keywords)
KO assignmentK03295
  Level 3 annotation:
    cation efflux system protein, CDF family
  Level 2 annotation:
    Other ion-coupled transporters
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 947 residues, 43561969-43564807Exon2: 47 residues, 43566100-43566235Exon3: 37 residues, 43567016-43567122Exon4: 69 residues, 43568330-43568532Exon5: 53 residues, 43570217-43570371Exon6: 51 residues, 43590627-43590774Exon7: 170 residues, 43601453-43601958Exon8: 68 residues, 43602096-43602294Exon9: 2 residues, -Jump to ZNT4_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 4169 43561969-43602294 ~-40K 12281(SLC30A4)(-)Loci: 2887 43666708-43689200 ~-22K 12285(PLDN)(+)Loci: 2888 43714547-43770770 ~-56K 12287(SQRDL)(+)Loci: 4168 43196978-43209349 ~-12K 12269(-)Link out to UCSC