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0ZNT3_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameSLC30A3
DescriptionZinc transporter 3 (znt-3) (solute carrier family 30 member 3).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005768 endosome (TAS)
0005887 integral to plasma membrane (TAS)
0005624 membrane fraction (TAS)
0008021 synaptic vesicle (TAS)
0015633 zinc porter activity (TAS)
0006810 transport (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Members of this family are integral membrane proteins.hatare found to increase tolerance to divalent metal ions suchas cadmium.inc.nd cobalt. These proteins are considered tobe efflux pumps that remove these ions from cells however others are implicated in ion uptake . The family has six predicted transmembrane domains. Members of the family are variable in length because of variably sized inserts.ften containing low-complexity sequence.
  IPR002524:Cation efflux protein
IPR002524:Cation_efflux 
Evalue:-85.6989669799805 
Location:76-376
SequencesProtein: ZNT3_HUMAN (388 aa)
mRNA: NM_003459
Local Annotation
Synapse Ontology
endosome of the presynaptic compartment. A cellular structure that is involved in the transport of proteins in the neuron after the proteins are endocytosed from the outside to the inside of the cell.
sdb:0088 endosome  (Evidence:keywords)
Various stages of the synaptic vesicle cycle, including attachment, prefusion, triggering, recycling and reloading of the vesicles with transmitter.
sdb:0098 synaptic vesicle cycling  (Evidence:keywords)
interaction between synaptic vesicle and the scaffold.
sdb:0106 transport of synaptic vesicle in the presynaptic axon  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 297 residues, 27330944-27331832Exon2: 47 residues, 27332757-27332892Exon3: 37 residues, 27333159-27333265Exon4: 68 residues, 27333525-27333724Exon5: 53 residues, 27334276-27334430Exon6: 51 residues, 27334532-27334679Exon7: 62 residues, 27335124-27335306Exon8: 95 residues, 27339183-27339464Exon9: 2 residues, -Jump to ZNT3_HUMAN  
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Loci Cluster (Details)Loci: 3152 27047028-27103590 ~-57K 20131(MAPRE3)(+)Loci: 3153 27155437-27162767 ~-7K 20145(EMILIN1)(+)Loci: 4428 27207130-27211046 ~-4K 20152(PREB)(-)Loci: 4429 27330944-27339464 ~-9K 20162(SLC30A3)(-)Loci: 3154 27446892-27453498 ~-7K 20173(SNX17)(+)Loci: 3155 27848089-27856103 ~-8K 20199(+)Loci: 3151 26924466-27024572 ~-100K 20130(DPYSL5)(+)Link out to UCSC