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0VPS54_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionVacuolar protein sorting protein 54 (tumor antigen slp-8p) (hepatocellular carcinoma protein 8).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family contains various proteins that are homologues of the yeast Vps54 protein.uch as the rat homolog ().he human homolog ().nd the mouse homolog (). In yeast.ps54 associates with Vps52 and Vps53 proteins to form a trimolecular complex that is involved in protein transport between Golgi.ndosomal.nd vacuolar compartments . All Vps54 homologues contain a coiled coil region (not found in the region featured in this family) and multiple dileucine motifs .
SequencesProtein: VPS54_HUMAN (977 aa)
mRNA: NM_016516
Local Annotation
Synapse Ontology
endosome of the presynaptic compartment. A cellular structure that is involved in the transport of proteins in the neuron after the proteins are endocytosed from the outside to the inside of the cell.
sdb:0088 endosome  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 335 residues, 63973171-63974173Exon2: 33 residues, 63978133-63978228Exon3: 38 residues, 63980111-63980219Exon4: 29 residues, 63992982-63993063Exon5: 42 residues, 63993177-63993299Exon6: 31 residues, 63993860-63993948Exon7: 37 residues, 63994819-63994925Exon8: 23 residues, 63997537-63997601Exon9: 39 residues, 64000520-64000633Exon10: 62 residues, 64001083-64001265Exon11: 45 residues, 64001843-64001973Exon12: 115 residues, 64014310-64014651Exon13: 34 residues, 64023102-64023199Exon14: 20 residues, 64025237-64025293Exon15: 38 residues, 64028020-64028128Exon16: 44 residues, 64029674-64029801Exon17: 130 residues, 64042695-64043081Exon18: 46 residues, 64046472-64046604Exon19: 13 residues, 64049594-64049629Exon20: 28 residues, 64052803-64052882Exon21: 82 residues, 64062283-64062525Exon22: 54 residues, 64064501-64064657Exon23: 49 residues, 64099575-64099718Exon24: 2 residues, -Jump to VPS54_HUMAN  
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