SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0VPS35_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameVPS35
DescriptionVacuolar protein sorting 35 (vesicle protein sorting 35) (hvps35) (maternal-embryonic 3).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005829 cytosol (IDA)
0005515 protein binding (IPI)
0042147 retrograde transport, endosome to Golgi (NAS)

Warning: fopen(/home/kongl/syndb/www/temp/1790866985.dot) [function.fopen]: failed to open stream: Permission denied in /home/kongl/syndb/www/sdb_pro.php on line 269

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 270

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 271

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 272

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 273

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 274

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 299

Warning: fclose(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 300
schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The movement of lipid and protein components between intracellular organelles requires the regulated interactions of manymolecules. Vacuolar protein sorting-associated protein (Vps)5 is a yeast protein that is a subunit of a large multimericcomplex.ermed the retromer complex.nvolved in retrograde transport of proteins from endosomes to the trans-Golgi network. Sorting nexin (SNX) 1 and SNX2 are its mammalian orthologs .To carry out its biological functions.ps5 forms the retromer complexwith at least four other proteins: Vps17.ps26.ps29.nd Vps35.Vps35 contains a central region of weaker sequence similarity.hought to indicate the presence of at least three domains .
  IPR005378:Vacuolar protein sorting-associated protein 35
IPR005378:Vps35 
Evalue:-1e+125 
Location:53-763
SequencesProtein: VPS35_HUMAN (796 aa)
mRNA: NM_018206
Local Annotation
Synapse Ontology
endosome of the presynaptic compartment. A cellular structure that is involved in the transport of proteins in the neuron after the proteins are endocytosed from the outside to the inside of the cell.
sdb:0088 endosome  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 325 residues, 45251091-45252064Exon2: 50 residues, 45253130-45253274Exon3: 82 residues, 45253655-45253895Exon4: 62 residues, 45254395-45254575Exon5: 43 residues, 45260342-45260465Exon6: 54 residues, 45263117-45263273Exon7: 71 residues, 45263677-45263885Exon8: 51 residues, 45265726-45265875Exon9: 34 residues, 45265976-45266073Exon10: 38 residues, 45267995-45268105Exon11: 30 residues, 45268727-45268811Exon12: 73 residues, 45270355-45270569Exon13: 63 residues, 45272083-45272266Exon14: 43 residues, 45272789-45272913Exon15: 34 residues, 45273491-45273588Exon16: 35 residues, 45274920-45275019Exon17: 18 residues, 45280543-45280593Exon18: 2 residues, -Jump to VPS35_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 4222 45672942-45735409 ~-62K 14040(NETO2)(-)Loci: 4221 45251091-45280593 ~-30K 14029(VPS35)(-)Link out to UCSC