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0VPS26_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameVPS26
DescriptionVacuolar protein sorting 26 (vesicle protein sorting 26) (hvps26).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005829 cytosol (IDA)
0005515 protein binding (IPI)
0008565 protein transporter activity (NAS)
0042147 retrograde transport, endosome to Golgi (NAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The movement of lipid and protein components between intracellular organelles requires the regulated interactions of many molecules. Vacuolar protein sorting-associated protein (Vps)5 is a yeast protein that is a subunit of a large multimeric complex.ermed the retromer complex.nvolved in retrograde transport of proteins from endosomes to the trans-Golgi network. Sorting nexin (SNX) 1 and SNX2 are its mammalian orthologs .To carry out its biological functions.ps5 forms the retromer complexwith at least four other proteins: Vps17.ps26.ps29.nd Vps35 . This family of Vps26-proteins also contains Down syndrome critical region 3/A.
  IPR005377:Vacuolar protein sorting-associated protein 26
IPR005377:Vps26 
Evalue:-217.638275146484 
Location:8-283
SequencesProtein: VPS26_HUMAN (327 aa)
mRNA: NM_004896
Local Annotation
Synapse Ontology
endosome of the presynaptic compartment. A cellular structure that is involved in the transport of proteins in the neuron after the proteins are endocytosed from the outside to the inside of the cell.
sdb:0088 endosome  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 44 residues, 70553913-70554042Exon2: 52 residues, 70562659-70562809Exon3: 27 residues, 70585573-70585649Exon4: 54 residues, 70586768-70586925Exon5: 57 residues, 70587808-70587973Exon6: 37 residues, 70592167-70592274Exon7: 25 residues, 70595803-70595872Exon8: 49 residues, 70598250-70598393Exon9: 569 residues, 70600917-70602620Exon10: 2 residues, -Jump to VPS26_HUMAN  
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Loci Cluster (Details)Loci: 2622 70748628-70831641 ~-83K 5039(HK1)(+)Loci: 3897 70834248-70846607 ~-12K 5040(TACR2)(-)Loci: 2621 70553913-70602620 ~-49K 5030(VPS26)(+)Link out to UCSC