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0VPS18_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameVPS18
DescriptionVacuolar protein sorting 18 (hvps18).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This region is found in a number of proteins identified as being involved in Golgi function and vacuolar sorting. The molecular function of this region is unknown. Proteins containing this domain also contain a C-terminal ring finger domain.
  IPR007810:Pep3/Vps18/deep orange
IPR007810:Pep3_Vps18 
Evalue:-75.5376052856445 
Location:291-436IPR001841:ZF_RING_1 
Evalue:0 
Location:0-0
SequencesProtein: VPS18_HUMAN (973 aa)
mRNA: NM_020857
Local Annotation
Synapse Ontology
endosome of the presynaptic compartment. A cellular structure that is involved in the transport of proteins in the neuron after the proteins are endocytosed from the outside to the inside of the cell.
sdb:0088 endosome  (Evidence:keywords)
priming for exocytosis prepares the calcium-dependent release and may involve partial fusion process. The vesicles are primed and become responsive to calcium.
sdb:0120 priming  (Evidence:keywords)
attachment of the vesicle filled with transmitters involves a specific interaction between the vesicle membrane and the presynaptic active zone.
sdb:0148 docking  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 144 residues, 38973919-38974349Exon2: 49 residues, 38975427-38975569Exon3: 32 residues, 38978396-38978488Exon4: 625 residues, 38978633-38980504Exon5: 455 residues, 38982105-38983464Exon6: 2 residues, -Jump to VPS18_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2873 38484977-38498355 ~-13K 12090(IVD)(+)Loci: 2874 38550504-38552645 ~-2K 12093(D4ST1)(+)Loci: 2875 38673738-38743829 ~-70K 12099(CASC5)(+)Loci: 2876 38843576-38847203 ~-4K 12107(GCHFR)(+)Loci: 2877 38973919-38983464 ~-10K 12116(VPS18)(+)Loci: 4163 38367401-38387330 ~-20K 12082(PLCB2)(-)Link out to UCSC