SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0TXLNA_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameTXLNA
DescriptionAlpha-taxilin.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005576 extracellular region (NAS)
0030372 high molecular weight B cell growth factor ... (NAS)
0005515 protein binding (IPI)
0008283 cell proliferation (NAS)

Warning: fopen(/home/kongl/syndb/www/temp/5174996.dot) [function.fopen]: failed to open stream: Permission denied in /home/kongl/syndb/www/sdb_pro.php on line 269

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 270

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 271

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 272

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 273

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 274

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 299

Warning: fclose(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 300
schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The Prefoldin/GimC family of proteins are found in eukaryotes and archaea . Prefoldin is part of a molecular chaperone system that promotes the correct folding of nascent polypeptide chains. Prefoldin/GimC interacts with the nascent chain to stabilise it prior to its folding within the central cavity of a chaperonin. Prefoldin/GimC is a hexamer consisting of two types of subunits.lpha and beta. Archaeal prefoldin contains one type of alpha and one type of beta subunit .hile eukaryotic prefoldin/GimC contains two different but related alpha subunits and four related beta subunits .The SSF signature in this entry is currently under review. Please be aware that some of the protein hits may be false positives.
  IPR009053:Prefoldin
Members of this family display a core structure consisting of a closed bundle of four helices in a left-handed twist.ith two crossover connections. Family members include long-chain cytokines.uch as leukaemia inhibitory factor (LIF) .he growth hormone somatotropin .nterleukin-6 and leptin ; short-chain cytokines.uch as erythropoietin .tem cell factor (SCF) .acrophage colony-stimulating factor (M-CSF) and interleukin-2.3.4.5 and -13; and interferons/interleukin-10.Please be aware that some of the protein hits may be false positives.
  IPR009079:Four-helical cytokine
IPR009079:4_helix_cytokine 
Evalue:0 
Location:165-279IPR009053:Prefoldin 
Evalue:0 
Location:357-447
SequencesProtein: TXLNA_HUMAN (546 aa)
mRNA: NM_175852
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords)
Typical ecretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of nonpeptide neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
sdb:0094 typical synaptic vesicle  (Evidence:keywords)
Various stages of the synaptic vesicle cycle, including attachment, prefusion, triggering, recycling and reloading of the vesicles with transmitter.
sdb:0098 synaptic vesicle cycling  (Evidence:keywords)
priming for exocytosis prepares the calcium-dependent release and may involve partial fusion process. The vesicles are primed and become responsive to calcium.
sdb:0120 priming  (Evidence:keywords)
attachment of the vesicle filled with transmitters involves a specific interaction between the vesicle membrane and the presynaptic active zone.
sdb:0148 docking  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 12 residues, 32417931-32417964Exon2: 69 residues, 32418501-32418702Exon3: 114 residues, 32419429-32419765Exon4: 32 residues, 32422712-32422804Exon5: 59 residues, 32426141-32426312Exon6: 67 residues, 32428242-32428437Exon7: 42 residues, 32430498-32430618Exon8: 27 residues, 32430844-32430919Exon9: 33 residues, 32431395-32431488Exon10: 34 residues, 32432252-32432348Exon11: 1129 residues, 32433089-32436472Exon12: 2 residues, -Jump to TXLNA_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 3788 31965305-32002223 ~-37K 944(BAI2)(-)Loci: 2501 32417931-32436472 ~-19K 964(TXLNA)(+)Loci: 2502 32489505-32524350 ~-35K 978(LCK)(+)Loci: 3789 32572027-32574410 ~-2K 982(MARCKSL1)(-)Loci: 2500 31857227-31865301 ~-8K 939(HCRTR1)(+)Link out to UCSC