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0TRI29_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameTRIM29
DescriptionTripartite motif protein 29 (ataxia-telangiectasia group d-associated protein).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0003700 transcription factor activity (TAS)
0006366 transcription from RNA polymerase II promoter (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The B-box zinc finger is an around 40 amino acids domain. One or two copies ofthis motif are generally associated with a ring finger and a coiled coil motifto form the so-called tripartite motif. It is found essentially intranscription factors.ibonucleoproteins and protooncoproteins.ut nofunction is clearly assigned to this domain . It has been shown to beessential but not sufficient to localize the PML protein in a punctate patternin interphase nuclei . Among the 7 possible ligands for the zinc atomcontained in a B-box.nly 4 are used and bind one zinc atom in a Cys2-His2tetrahedral arrangement. The NMR analysis reveals that the B-box structurecomprises two beta-strands.wo helical turns and three extended loop regionsdifferent from any other zinc binding motif .
  IPR000315:Zinc finger, B-box
IPR000315:zf-B_box 
Evalue:-13.795880317688 
Location:220-260
SequencesProtein: TRI29_HUMAN (588 aa)
mRNA: NM_012101 NM_058193
Local Annotation
Synapse Ontology
intermediate filaments of the presynaptic compartments. Both microtubles and intermediate filaments represent the main structural scaffold of axons.
sdb:0086 intermediate filaments  (Evidence:keywords)
activation of protein kinase C
sdb:0206 activation of protein kinase C  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 397 residues, 119487204-119488394Exon2: 27 residues, 119491255-119491332Exon3: 35 residues, 119494140-119494239Exon4: 33 residues, 119496490-119496583Exon5: 36 residues, 119498871-119498973Exon6: 68 residues, 119501608-119501807Exon7: 80 residues, 119503253-119503487Exon8: 34 residues, 119504317-119504413Exon9: 311 residues, 119513145-119514073Exon10: 2 residues, -Jump to TRI29_HUMANExon1: 58 residues, 119487204-119487376Exon2: 27 residues, 119488317-119488394Exon3: 41 residues, 119489454-119489573Exon4: 27 residues, 119491255-119491332Exon5: 35 residues, 119494140-119494239Exon6: 33 residues, 119496490-119496583Exon7: 36 residues, 119498871-119498973Exon8: 68 residues, 119501608-119501807Exon9: 80 residues, 119503253-119503487Exon10: 34 residues, 119504317-119504413Exon11: 311 residues, 119513145-119514073Exon12: 2 residues, -Jump to TRI29_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2714 119616255-119695863 ~-80K 7934(POU2F3)(+)Loci: 2715 119713155-119865855 ~-153K 7937(ARHGEF12)(+)Loci: 4000 119487204-119514073 ~-27K 7930(TRIM29)(-)Link out to UCSC