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0TEKT2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionTektin-2 (testicular tektin) (tektin-t) (testicular tektin b1-like protein) (tektin-b1) (tektb1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Tektin heteropolymers form unique protofilaments of flagellar microtubules. The proteins are predicted to form extended rods composed of 2 alpha-helical segments (~180 residues long) capable of forming coiled coils.nterrupted by non-helical linkers . The 2 segments are similar in sequence.ndicating a gene duplication event. Along each tektin rod.ysteine residues occur with a periodicity of ~8nm.oincident with theaxial repeat of tubulin dimers in microtubules . It is proposed thatthe assembly of tektin heteropolymers produces filaments with repeats of8. and 96nm.enerating the basis for the complexspatial arrangements of axonemal components .
SequencesProtein: TEKT2_HUMAN (430 aa)
mRNA: NM_014466
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 26 residues, 36322262-36322337Exon2: 71 residues, 36323057-36323265Exon3: 44 residues, 36323350-36323476Exon4: 70 residues, 36324023-36324229Exon5: 50 residues, 36324891-36325035Exon6: 40 residues, 36325118-36325233Exon7: 38 residues, 36325391-36325499Exon8: 50 residues, 36325626-36325770Exon9: 28 residues, 36325915-36325995Exon10: 102 residues, 36326160-36326462Exon11: 2 residues, -Jump to TEKT2_HUMAN  
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