SynDB Home Page
SynDB Home Page

blue bulletSynDB protein details  

Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0TACC2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionTransforming acidic coiled-coil-containing protein 2 (anti zuai-1) (azu-1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family contains the proteins TACC 1. and 3.ound concentrated in the centrosomes of eukaryotes which may play a conserved role in organising centrosomal microtubules. The human TACC proteins have been linked to cancer and TACC2 has been identified as a possible tumour suppressor (AZU-1) .
  IPR007707:Transforming acidic coiled-coil-containing
SequencesProtein: TACC2_HUMAN (1026 aa)
mRNA: NM_006997
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 135 residues, 123913094-123913497Exon2: 47 residues, 123944544-123944681Exon3: 439 residues, 123959901-123961213Exon4: 22 residues, 123964895-123964956Exon5: 69 residues, 123966131-123966333Exon6: 22 residues, 123974230-123974292Exon7: 40 residues, 123975870-123975986Exon8: 59 residues, 123977341-123977513Exon9: 49 residues, 123978850-123978991Exon10: 32 residues, 123979855-123979945Exon11: 50 residues, 123986899-123987043Exon12: 27 residues, 123987465-123987542Exon13: 16 residues, 123991462-123991506Exon14: 55 residues, 123998147-123998308Exon15: 37 residues, 123998554-123998661Exon16: 42 residues, 123999048-123999169Exon17: 185 residues, 124003495-124004045Exon18: 2 residues, -Jump to TACC2_HUMAN  
Tune and view alternative isoforms