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0STMN1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameSTMN1
DescriptionStathmin (phosphoprotein p19) (pp19) (oncoprotein 18) (op18) (leukemia-associated phosphoprotein p18) (pp17) (prosolin) (metablastin) (pr22 protein).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0004871 signal transducer activity (TAS)
0007242 intracellular signaling cascade (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Stathmin is a ubiquitous phosphorylated protein thought to act as an intracellular relay for diverse regulatory pathways .unctioning through a variety of second messengers. Its phosphorylation and gene expression are regulated throughout development and in response to extracellular signals regulating cell proliferation.ifferentiation and function . Stathmin.nd the related proteins SCG10 and XB3.ontain a N-terminal domain (XB3 contains an additional N-terminal hydrophobic region). 78 amino acid coiled-coil region.nd a short C-terminal domain.
  IPR000956:Stathmin
IPR000956:Stathmin 
Evalue:-90.6575775146484 
Location:3-142
SequencesProtein: STMN1_HUMAN (148 aa)
mRNA: NM_203401
Local Annotation
Synapse Ontology
transport of vesicles in the presynaptic neuron
sdb:0017 Mobilization: synapsins, CAM kinase I  (Evidence:keywords)
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 324 residues, 26099194-26100165Exon2: 66 residues, 26100568-26100760Exon3: 59 residues, 26102718-26102891Exon4: 27 residues, 26103741-26103816Exon5: 102 residues, 26104929-26105231Exon6: 2 residues, -Jump to STMN1_HUMAN  
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Loci Cluster (Details)Loci: 3784 26099194-26105231 ~-6K 763(STMN1)(-)Loci: 3785 26159901-26197235 ~-37K 764(PAFAH2)(-)Loci: 2492 25742752-25767962 ~-25K 748(LDLRAP1)(+)Link out to UCSC