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0SNIP_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameP140
Descriptionp130cas-associated protein (p140cap) (snap-25-interacting protein) (snip).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain ArchitectureN/A
SequencesProtein: SNIP_HUMAN (1055 aa)
mRNA: AK126665 NM_025248
Local Annotation
Synapse Ontology
Fusion of intracellular membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.
sdb:0049 synaptic vesicle fusion  (Evidence:keywords)
Secretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of nonpeptide neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
sdb:0074 synaptic vesicle  (Evidence:keywords)
priming for exocytosis prepares the calcium-dependent release and may involve partial fusion process. The vesicles are primed and become responsive to calcium.
sdb:0120 priming  (Evidence:keywords)
attachment of the vesicle filled with transmitters involves a specific interaction between the vesicle membrane and the presynaptic active zone.
sdb:0148 docking  (Evidence:keywords)
the plasma membrane is thicked into an active zone to which several synaptic vesicles are attached.
sdb:0151 active zone  (Evidence:keywords)
?
sdb:0328 transmitters release and endocytosis  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 81 residues, 33941330-33941570Exon2: 78 residues, 33942964-33943192Exon3: 51 residues, 33953583-33953730Exon4: 53 residues, 33958318-33958471Exon5: 53 residues, 33958817-33958972Exon6: 80 residues, 33960916-33961151Exon7: 84 residues, 33961647-33961894Exon8: 51 residues, 33962208-33962356Exon9: 45 residues, 33962486-33962617Exon10: 60 residues, 33967988-33968164Exon11: 64 residues, 33969346-33969534Exon12: 16 residues, 33969815-33969859Exon13: 33 residues, 33970094-33970187Exon14: 290 residues, 33971224-33972090Exon15: 33 residues, 33972588-33972682Exon16: 68 residues, 33973084-33973283Exon17: 67 residues, 33973879-33974075Exon18: 9 residues, 33977984-33978005Exon19: 102 residues, 33988268-33988570Exon20: 84 residues, 34015462-34015709Exon21: 2 residues, -Jump to SNIP_HUMANExon1: 618 residues, 33951044-33952897Exon2: 51 residues, 33953583-33953730Exon3: 53 residues, 33958318-33958471Exon4: 53 residues, 33958817-33958972Exon5: 80 residues, 33960916-33961151Exon6: 84 residues, 33961647-33961894Exon7: 51 residues, 33962208-33962356Exon8: 45 residues, 33962486-33962617Exon9: 60 residues, 33967988-33968164Exon10: 64 residues, 33969346-33969534Exon11: 16 residues, 33969815-33969859Exon12: 33 residues, 33970094-33970187Exon13: 290 residues, 33971224-33972090Exon14: 33 residues, 33972588-33972682Exon15: 226 residues, 33973084-33973758Exon16: 2 residues, -Jump to SNIP_HUMAN  
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