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0SFXN2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameSFXN2
DescriptionSideroflexin-2.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
The MTC family consists of a limited number of homologues.ll from eukaryotes. One member of the family has been functionally characterized as a tricarboxylate carrier from rat liver mitochondria. The rat liver mitochondrial tricarboxylate carrier has been reported to transport citrate.is-aconitate.hreo-D-isocitrate.- and L-tartrate.alate.uccinate and phosphoenolpyruvate. It presumably functions by a proton symport mechanism. The rest of the characterized proteins appear to be sideroflexins involved in iron transport.
  IPR004686:Tricarboxylate/iron carrier
IPR004686:Mtc 
Evalue:-171.552841186523 
Location:15-322
SequencesProtein: SFXN2_HUMAN (322 aa)
mRNA: NM_178858
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 48 residues, 104464287-104464428Exon2: 64 residues, 104476358-104476544Exon3: 59 residues, 104476733-104476904Exon4: 35 residues, 104478177-104478276Exon5: 27 residues, 104479065-104479141Exon6: 30 residues, 104479469-104479555Exon7: 22 residues, 104481469-104481530Exon8: 24 residues, 104481898-104481965Exon9: 18 residues, 104482605-104482655Exon10: 18 residues, 104483300-104483350Exon11: 18 residues, 104485608-104485656Exon12: 509 residues, 104487409-104488932Exon13: 2 residues, -Jump to SFXN2_HUMAN  
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