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0SEPT5_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameSEPT5
DescriptionSeptin-5 (peanut-like protein 1) (cell division control related protein 1) (cdcrel-1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005886 plasma membrane (IDA)
0008021 synaptic vesicle (IDA)
0003924 GTPase activity (TAS)
0005515 protein binding (IPI)
0005198 structural molecule activity (TAS)
0000910 cytokinesis (TAS)
0017157 regulation of exocytosis (IMP)
0016080 synaptic vesicle targeting (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Members of this family are involved in cell division and bind GTP.Members of this family include the cell division control proteins CDC3.DC10.DC11 and CDC12/Septin and some uncharacterised proteins involved in cytokinesis.
  IPR000038:Cell division/GTP binding protein
IPR000038:Septin 
Evalue:-189.251815795898 
Location:41-321
SequencesProtein: SEPT5_HUMAN (369 aa)
mRNA: NM_002688 Y11593
Local Annotation
Synapse Ontology
Various stages of the synaptic vesicle cycle, including attachment, prefusion, triggering, recycling and reloading of the vesicles with transmitter.
sdb:0098 synaptic vesicle cycling  (Evidence:keywords)
KO assignmentK04557
  Level 3 annotation:
    peanut-like protein 1 (cell division control related protein 1)
  Level 2 annotation:
    Parkinson's disease
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 57 residues, 18081986-18082154Exon2: 5 residues, 18082303-18082314Exon3: 34 residues, 18087124-18087221Exon4: 31 residues, 18087328-18087415Exon5: 43 residues, 18087637-18087761Exon6: 47 residues, 18087842-18087977Exon7: 41 residues, 18088071-18088189Exon8: 36 residues, 18088290-18088392Exon9: 34 residues, 18089162-18089259Exon10: 47 residues, 18089344-18089480Exon11: 36 residues, 18089759-18089862Exon12: 299 residues, 18089950-18090842Exon13: 2 residues, -Jump to SEPT5_HUMANExon1: 30 residues, 18082066-18082154Exon2: 5 residues, 18082303-18082314Exon3: 33 residues, 18087124-18087218Exon4: 32 residues, 18087325-18087415Exon5: 43 residues, 18087637-18087761Exon6: 47 residues, 18087842-18087977Exon7: 41 residues, 18088071-18088189Exon8: 36 residues, 18088290-18088392Exon9: 34 residues, 18089162-18089259Exon10: 47 residues, 18089344-18089480Exon11: 36 residues, 18089759-18089862Exon12: 299 residues, 18089950-18090842Exon13: 2 residues, -Jump to SEPT5_HUMAN  
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Loci Cluster (Details)Loci: 4555 16596905-16637258 ~-40K 24143(BID)(-)Loci: 3295 16973558-16994498 ~-21K 24153(TUBA8)(+)Loci: 4556 17280294-17304066 ~-24K 24158(PRODH)(-)Loci: 4557 17543094-17546285 ~-3K 24164(SLC25A1)(-)Loci: 4558 17698223-17799219 ~-101K 24167(HIRA)(-)Loci: 3296 18081986-18090842 ~-9K 24176(SEPT5)(+)Loci: 4559 18243045-18309515 ~-66K 24188(TXNRD2)(-)Loci: 3297 18309308-18336528 ~-27K 24191(COMT)(+)Loci: 3294 16423182-16453647 ~-30K 24138(SLC25A18)(+)Link out to UCSC