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0SCAM5_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameSCAMP5
DescriptionSecretory carrier-associated membrane protein 5 (secretory carrier membrane protein 5).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
In vertebrates.ecretory carrier membrane proteins (SCAMPs) 1-3 constitute a family of putative membrane-trafficking proteins composed of cytoplasmic N-terminal sequences with NPF repeats.our central transmembrane regions (TMRs).nd a cytoplasmic tail. SCAMPs probably function in endocytosis by recruiting EH-domain proteins to the N-terminal NPF repeats but may have additional functions mediated by their other sequences .
  IPR007273:SCAMP
IPR007273:SCAMP 
Evalue:-110.200660705566 
Location:4-180
SequencesProtein: SCAM5_HUMAN (235 aa)
mRNA: AL834226 NM_138967
Local Annotation
Synapse Ontology
Fusion of intracellular membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.
sdb:0049 synaptic vesicle fusion  (Evidence:keywords)
Various stages of the synaptic vesicle cycle, including attachment, prefusion, triggering, recycling and reloading of the vesicles with transmitter.
sdb:0098 synaptic vesicle cycling  (Evidence:keywords)
interaction between synaptic vesicle and the scaffold.
sdb:0106 transport of synaptic vesicle in the presynaptic axon  (Evidence:keywords)
?
sdb:0328 transmitters release and endocytosis  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 39 residues, 73074953-73075067Exon2: 20 residues, 73091185-73091240Exon3: 45 residues, 73092070-73092199Exon4: 54 residues, 73095986-73096143Exon5: 36 residues, 73097263-73097365Exon6: 41 residues, 73097811-73097929Exon7: 904 residues, 73098182-73100889Exon8: 2 residues, -Jump to SCAM5_HUMANExon1: 37 residues, 73074957-73075067Exon2: 20 residues, 73091185-73091240Exon3: 45 residues, 73092070-73092199Exon4: 54 residues, 73095986-73096143Exon5: 36 residues, 73097263-73097365Exon6: 49 residues, 73097787-73097929Exon7: 903 residues, 73098182-73100887Exon8: 2 residues, -Jump to SCAM5_HUMAN  
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Loci Cluster (Details)Loci: 4180 73034698-73036146 ~-1K 12752(-)Loci: 2900 73074953-73100889 ~-26K 12753(SCAMP5)(+)Loci: 2899 72687765-72709510 ~-22K 12733(CLK3)(+)Link out to UCSC