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0RNZ1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameELAC1
DescriptionZinc phosphodiesterase elac protein 1 (ec 3.1.26.11) (ribonuclease z 1) (rnase z 1) (trnase z 1) (trna 3 endonuclease 1) (elac homolog protein 1) (deleted in ma29).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Apart from the beta-lactamases a number of other proteins contain this domain . These proteins include thiolesterases.embers of the glyoxalase II family.hat catalyse the hydrolysis of S-D-lactoyl-glutathione to form glutathione and D-lactic acid and a competence protein that is essential for natural transformation in Neisseria gonorrhoeae and could be a transporter involved in DNA uptake. Except for the competence protein these proteins bind two zinc ions per molecule as cofactor.
  IPR001279:Beta-lactamase-like
IPR001279:Lactamase_B 
Evalue:-13.5686359405518 
Location:20-75
SequencesProtein: RNZ1_HUMAN (363 aa)
mRNA: NM_018696
Local Annotation
Synapse Ontology
?
sdb:0265 cAMP mediated STP  (Evidence:keywords)
KO assignmentK00784
  Level 3 annotation:
    ribonuclease Z
  Level 2 annotation:
    Other enzymes
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 33 residues, 46748384-46748482Exon2: 57 residues, 46754764-46754929Exon3: 158 residues, 46764463-46764931Exon4: 502 residues, 46766986-46768487Exon5: 2 residues, -Jump to RNZ1_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 3067 46748384-46768487 ~-20K 17312(ELAC1)(+)Loci: 3066 46659432-46728256 ~-69K 17310(ME2)(+)Link out to UCSC