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1Q9UJJ7_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionOtthump00000045508 (ribosomal large subunit pseudouridine synthase c like) (rna pseudouridylate synthase domain containing 1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0009982 pseudouridine synthase activity (IEA)
0003723 RNA binding (IEA)
0006396 RNA processing (IEA)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Pseudouridine synthases are responsible for synthesis of pseudouridine from uracil in 23S rRNA.Proteins belonging to the family of pseudouridine synthases have been shown to share regions ofsimilarities . These include Escherichia coli and Haemophilus influenzae ribosomal large subunitpseudouridine synthase A (gene rluA). (gene rluC) and D (gene rluD); yeast DRAP deaminase(gene RIB2); Escherichia coli hypothetical protein yqcB and HI1435.he corresponding Haemophilus influenzae protein;Bacillus subtilis hypothetical proteins yhcT.jbO and ylyB; Helicobacter pylori hypothetical proteins HP0347;HP0745 and HP0956; Mycoplasma genitalium hypothetical proteins MG209 and MG370; Synechocystis strainPCC 6803 hypothetical proteins slr1592 and slr1629; yeast hypothetical proteins YDL036c.GR169c andSpAC18B11.02c; and Caenorhabditis elegans hypothetical protein K07E8.7. These are proteins of from 21 to 50 kDa whichcontain a number of conserved regions in their central section. This domain includes members of both the Rsu and Rlu families.
  IPR006145:Pseudouridine synthase
IPR006145:PseudoU_synth_2 
Evalue:-15.6020603179932 
Location:17-182
SequencesProtein: Q9UJJ7_HUMAN (312 aa)
mRNA: NM_058192
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 468 residues, 774975-776378Exon2: 36 residues, 776827-776929Exon3: 36 residues, 777077-777180Exon4: 43 residues, 777354-777478Exon5: 65 residues, 777556-777745Exon6: 44 residues, 778256-778384Exon7: 2 residues, -Jump to Q9UJJ7_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2909 387192-390754 ~-4K 13162(NME4)(+)Loci: 2910 415668-512481 ~-97K 13166(RAB11FIP3)(+)Loci: 2911 580179-619272 ~-39K 13173(RAB40C)(+)Loci: 4199 774975-778384 ~-3K 13216(-)Loci: 2912 1143241-1211772 ~-69K 13223(CACNA1H)(+)Loci: 2913 1324663-1339443 ~-15K 13234(BAIAP3)(+)Loci: 4200 1435345-1465013 ~-30K 13244(CLCN7)(-)Loci: 2914 1696221-1760318 ~-64K 13253(MAPK8IP3)(+)Loci: 2915 1979968-1984276 ~-4K 13288(SYNGR3)(+)Loci: 2916 2016896-2028484 ~-12K 13290(SLC9A3R2)(+)Loci: 2917 2038599-2078713 ~-40K 13294(TSC2)(+)Loci: 2918 2138651-2144141 ~-5K 13300(RAB26)(+)Loci: 4201 2167184-2186466 ~-19K 13303(CASKIN1)(-)Loci: 4198 357394-360541 ~-3K 13159(MRPL28)(-)Link out to UCSC