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1Q9NPE2_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionMesenchymal stem cell protein dsc92 (spinal cord-derived protein fi58g) (hypothetical protein dkfzp566l1946) (ngrn protein).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005634 nucleus (NAS)
0030182 neuron differentiation (NAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family consists of several mouse and human neugrin proteins. Neugrin and m-neugrin are mainly expressed in neurons in the nervous system.nd are thought to play an important role in the process of neuronal differentiation .
  IPR010487:Neugrin
Homeodomain proteins are transcription factors that share a related DNA binding homeodomain . The homeodomain was first identified in a number of Drosophila homeotic and segmentation proteins.ut is now known to be well conserved in many other animals.ncluding vertebrates. The domain binds DNA through a helix-turn-helix (HTH) structure. The HTH motif is characterised by two alpha-helices.hich make intimate contacts with the DNA and are joined by a short turn. The second helix binds to DNA via a number of hydrogen bonds and hydrophobic interactions.hich occur between specific side chains and the exposed bases and thymine methyl groups within the major groove of the DNA. The first helix helps to stabilise the structure. Many proteins contain homeodomains.ncluding Drosophila Engrailed.east mating type proteins.epatocyte nuclear factor 1a and HOX proteins.The homeodomain motif is very similar in sequence and structure to domains in a wide range of DNA-binding proteins.ncluding recombinases.yb proteins.ARP response regulators.uman telomeric proteins (hTRF1).aired domain proteins (PAX).east RAP1.entromere-binding proteins CENP-B and ABP-1.ranscriptional regulators (TyrR).raC-type transcriptional activators.nd tetracycline repressor-like proteins (TetR.acR.cdC) .
  IPR009057:Homeodomain-like
IPR010487:Neugrin 
Evalue:-176.154907226562 
Location:1-219
SequencesProtein: Q9NPE2_HUMAN (219 aa)
mRNA: NM_016645
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 246 residues, 88609898-88610634Exon2: 343 residues, 88615423-88616447Exon3: 2 residues, -Jump to Q9NPE2_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 4193 88008602-88023595 ~-15K 12995(PLIN)(-)Loci: 4194 88129129-88150938 ~-22K 13000(ANPEP)(-)Loci: 4195 88177792-88238206 ~-60K 13001(AP3S2)(-)Loci: 2905 88609898-88616447 ~-7K 13015(+)Loci: 4196 88691822-88693673 ~-2K 13016(GABARAPL3)(-)Loci: 2906 88732476-88846479 ~-114K 13020(IQGAP1)(+)Loci: 4192 87660562-87679030 ~-18K 12989(POLG)(-)Link out to UCSC