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1Q8TAL9_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionSolute carrier family 22 (organic cation transporter), member 15.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0016021 integral to membrane (IEA)
0005215 transporter activity (IEA)
0006810 transport (IEA)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Among the different families of transporter only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superfamily and the Major Facilitator Superfamily (MFS). The MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients .
  IPR011701:Major facilitator superfamily MFS_1
IPR011701:MFS_1 
Evalue:-12.8239088058472 
Location:99-446
SequencesProtein: Q8TAL9_HUMAN (535 aa)
mRNA: NM_018420
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentK08211
  Level 3 annotation:
    MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 15
  Level 2 annotation:
    Major facilitator superfamily (MFS)
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 72 residues, 116320644-116320858Exon2: 73 residues, 116336174-116336387Exon3: 46 residues, 116363725-116363858Exon4: 57 residues, 116364864-116365029Exon5: 45 residues, 116371036-116371166Exon6: 74 residues, 116375509-116375725Exon7: 49 residues, 116379330-116379471Exon8: 30 residues, 116381446-116381532Exon9: 42 residues, 116406905-116407026Exon10: 26 residues, 116408579-116408652Exon11: 65 residues, 116410663-116410852Exon12: 797 residues, 116411162-116413548Exon13: 2 residues, -Jump to Q8TAL9_HUMAN  
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Loci Cluster (Details)Loci: 2542 116717358-116748917 ~-32K 2272(ATP1A1)(+)Loci: 2541 116320644-116413548 ~-93K 2268(+)Link out to UCSC