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1Q8NDX2_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionVesicular glutamate transporter 3.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0016021 integral to membrane (IEA)
0005215 transporter activity (IEA)
0006810 transport (IEA)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Among the different families of transporter only two occur ubiquitously in all classifications of organisms. These are the ATP-Binding Cassette (ABC) superfamily and the Major Facilitator Superfamily (MFS). The MFS transporters are single-polypeptide secondary carriers capable only of transporting small solutes in response to chemiosmotic ion gradients .
  IPR011701:Major facilitator superfamily MFS_1
IPR011701:MFS_1 
Evalue:-40.5376014709473 
Location:82-473
SequencesProtein: Q8NDX2_HUMAN (589 aa)
mRNA: NM_139319
Local Annotation
Synapse Ontology
Typical ecretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of nonpeptide neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
sdb:0094 typical synaptic vesicle  (Evidence:keywords)
Various stages of the synaptic vesicle cycle, including attachment, prefusion, triggering, recycling and reloading of the vesicles with transmitter.
sdb:0098 synaptic vesicle cycling  (Evidence:keywords)
KO assignmentK08193
  Level 3 annotation:
    MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)
  Level 2 annotation:
    Major facilitator superfamily (MFS)
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 93 residues, 99275124-99275401Exon2: 86 residues, 99298609-99298862Exon3: 41 residues, 99308909-99309028Exon4: 40 residues, 99311277-99311392Exon5: 31 residues, 99314238-99314326Exon6: 31 residues, 99319685-99319772Exon7: 48 residues, 99320248-99320388Exon8: 52 residues, 99320504-99320654Exon9: 46 residues, 99321946-99322079Exon10: 39 residues, 99330678-99330789Exon11: 44 residues, 99335937-99336065Exon12: 750 residues, 99337723-99339967Exon13: 2 residues, -Jump to Q8NDX2_HUMAN  
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Loci Cluster (Details)Loci: 2781 99275124-99339967 ~-65K 9512(+)Loci: 2782 99491619-99542814 ~-51K 9516(GAS2L3)(+)Loci: 4067 98987818-99060773 ~-73K 9498(-)Link out to UCSC