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1Q86T80_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionHypothetical protein dkfzp451m0318.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain ArchitectureN/A
SequencesProtein: Q86T80_HUMAN (367 aa)
mRNA: AL832648
Local Annotation
Synapse Ontology
Fusion of intracellular membrane-bound vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.
sdb:0049 synaptic vesicle fusion  (Evidence:domains)
priming for exocytosis prepares the calcium-dependent release and may involve partial fusion process. The vesicles are primed and become responsive to calcium.
sdb:0120 priming  (Evidence:domains)
attachment of the vesicle filled with transmitters involves a specific interaction between the vesicle membrane and the presynaptic active zone.
sdb:0148 docking  (Evidence:domains)
?
sdb:0328 transmitters release and endocytosis  (Evidence:domains)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 34 residues, 8279988-8280088Exon2: 34 residues, 8288302-8288400Exon3: 53 residues, 8289753-8289907Exon4: 51 residues, 8290796-8290945Exon5: 47 residues, 8292592-8292729Exon6: 60 residues, 8294822-8294996Exon7: 32 residues, 8298838-8298930Exon8: 52 residues, 8304051-8304203Exon9: 208 residues, 8324507-8325125Exon10: 347 residues, 8325194-8326231Exon11: 930 residues, 8327612-8330396Exon12: 2 residues, -Jump to Q86T80_HUMAN  
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Loci Cluster (Details)Loci: 4258 6644024-6675784 ~-32K 14997(TEKT1)(-)Loci: 4259 7033935-7063745 ~-30K 15014(DLG4)(-)Loci: 2974 7063876-7069308 ~-5K 15016(ACADVL)(+)Loci: 4260 7084462-7086477 ~-2K 15021(GABARAP)(-)Loci: 2975 7252225-7263903 ~-12K 15047(NLGN2)(+)Loci: 2976 7289129-7301655 ~-13K 15051(CHRNB1)(+)Loci: 2977 7427889-7432228 ~-4K 15066(MPDU1)(+)Loci: 2978 7474184-7477419 ~-3K 15071(SHBG)(+)Loci: 4261 7512446-7531642 ~-19K 15074(TP53)(-)Loci: 4262 7774391-7775983 ~-2K 15094(TRAPPC1)(-)Loci: 2979 7846716-7864382 ~-18K 15097(GUCY2D)(+)Loci: 4263 8004447-8006987 ~-3K 15108(VAMP2)(-)Loci: 2980 8093361-8114528 ~-21K 15119(PFAS)(+)Loci: 2981 8279988-8330396 ~-50K 15135(+)Loci: 2973 6620295-6631688 ~-11K 14996(FBXO39)(+)Link out to UCSC