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1Q6ZRQ2_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionHypothetical protein flj46185.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0030286 dynein complex (IEA)
0003777 microtubule motor activity (IEA)
0007018 microtubule-based movement (IEA)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Dynein is a multisubunit microtubule-dependent motor enzyme that acts as the force generating protein of eukaryotic cilia and flagella. The cytoplasmic isoform of dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein is composed of a number of ATP-binding large subunits.ntermediate size subunits and small subunits (see ). This family represents the C-terminal region of dynein heavy chain. The dynein heavy chain also exhibits ATPase activity and microtubule binding ability and acts as a motor for the movement of organelles and vesicles along microtubules.
  IPR004273:Dynein heavy chain
IPR004273:Dynein_heavy 
Evalue:-1e+125 
Location:217-821
SequencesProtein: Q6ZRQ2_HUMAN (821 aa)
mRNA: AK128065
Local Annotation
Synapse Ontology
The directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
sdb:0057 axon transport  (Evidence:keywords)
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
It carries vesicles and organelles from the soma toward the axon terminal (anterograde transport) or vesicles containing sampled extracellular material from the terminal to the soma (retrograde transport)
sdb:0244 organelle and vesicle transport  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 153 residues, 73931373-73931829Exon2: 77 residues, 73933021-73933247Exon3: 50 residues, 73934132-73934276Exon4: 63 residues, 73934601-73934784Exon5: 63 residues, 73936200-73936383Exon6: 62 residues, 73936796-73936976Exon7: 66 residues, 73941704-73941896Exon8: 78 residues, 73945317-73945545Exon9: 44 residues, 73946766-73946894Exon10: 51 residues, 73948727-73948876Exon11: 66 residues, 73952280-73952474Exon12: 43 residues, 73953234-73953357Exon13: 59 residues, 73957090-73957261Exon14: 49 residues, 73957930-73958071Exon15: 57 residues, 73958358-73958523Exon16: 70 residues, 73959145-73959350Exon17: 43 residues, 73961019-73961142Exon18: 80 residues, 73962146-73962382Exon19: 66 residues, 73963320-73963513Exon20: 40 residues, 73966241-73966357Exon21: 71 residues, 73966677-73966885Exon22: 74 residues, 73967460-73967678Exon23: 34 residues, 73967838-73967934Exon24: 57 residues, 73969220-73969385Exon25: 80 residues, 73970520-73970754Exon26: 46 residues, 73974331-73974464Exon27: 2 residues, -Jump to Q9UFH2_HUMANExon1: 151 residues, 73931377-73931829Exon2: 84 residues, 73933021-73933267Exon3: 50 residues, 73934132-73934276Exon4: 63 residues, 73934601-73934784Exon5: 63 residues, 73936200-73936383Exon6: 62 residues, 73936796-73936976Exon7: 66 residues, 73941704-73941896Exon8: 78 residues, 73945317-73945545Exon9: 44 residues, 73946766-73946894Exon10: 51 residues, 73948727-73948876Exon11: 66 residues, 73952280-73952474Exon12: 43 residues, 73953234-73953357Exon13: 59 residues, 73957090-73957261Exon14: 49 residues, 73957930-73958071Exon15: 57 residues, 73958358-73958523Exon16: 70 residues, 73959145-73959350Exon17: 54 residues, 73960986-73961142Exon18: 80 residues, 73962146-73962382Exon19: 66 residues, 73963320-73963513Exon20: 48 residues, 73966241-73966381Exon21: 71 residues, 73966677-73966885Exon22: 74 residues, 73967460-73967678Exon23: 34 residues, 73967838-73967934Exon24: 57 residues, 73969220-73969385Exon25: 80 residues, 73970520-73970754Exon26: 56 residues, 73974331-73974493Exon27: 91 residues, 73976293-73976560Exon28: 39 residues, 73980338-73980451Exon29: 2 residues, -Jump to Q6ZRQ2_HUMANExon1: 151 residues, 73931377-73931829Exon2: 77 residues, 73933021-73933247Exon3: 50 residues, 73934132-73934276Exon4: 63 residues, 73934601-73934784Exon5: 63 residues, 73936200-73936383Exon6: 62 residues, 73936796-73936976Exon7: 66 residues, 73941704-73941896Exon8: 78 residues, 73945317-73945545Exon9: 44 residues, 73946766-73946894Exon10: 51 residues, 73948727-73948876Exon11: 66 residues, 73952280-73952474Exon12: 43 residues, 73953234-73953357Exon13: 59 residues, 73957090-73957261Exon14: 49 residues, 73957930-73958071Exon15: 57 residues, 73958358-73958523Exon16: 70 residues, 73959145-73959350Exon17: 43 residues, 73961019-73961142Exon18: 80 residues, 73962146-73962382Exon19: 66 residues, 73963320-73963513Exon20: 40 residues, 73966241-73966357Exon21: 71 residues, 73966677-73966885Exon22: 74 residues, 73967460-73967678Exon23: 34 residues, 73967838-73967934Exon24: 57 residues, 73969220-73969385Exon25: 80 residues, 73970520-73970754Exon26: 40 residues, 73974331-73974446Exon27: 2 residues, -Jump to Q9UFH2_HUMAN  
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Loci Cluster (Details)Loci: 3043 73721871-73733310 ~-11K 16728(BIRC5)(+)Loci: 4320 73931373-73980451 ~-49K 16737(-)Loci: 3042 73676265-73680604 ~-4K 16723(SYNGR2)(+)Link out to UCSC