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1Q6PI73_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionLilrb2 protein.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This entry represents domains with an immunoglobulin-like (Ig-like) fold.hich consists of a beta-sandwich of seven or more strands in two sheets with a Greek-key topology. Ig-like domains are one of the most common protein modules found in animals.ccurring in a variety of different proteins. These domains are often involved in interactions.ommonly with other Ig-like domains via their beta-sheets . Domains within this fold-family share the same structure.ut can diverge with respect to their sequence. Based on sequence.g-like domains can be classified as V-set domains (antibody variable domain-like).1-set domains (antibody constant domain-like).2-set domains.nd I-set domains (antibody intermediate domain-like). Proteins can contain more than one of these types of Ig-like domains. For example.n the human T-cell receptor antigen CD2.omain 1 (D1) is a V-set domain.hile domain 2 (D2) is a C2-set domain.oth domains having the same Ig-like fold .Domains with an Ig-like fold can be found in many.iverse proteins in addition to immunoglobulin molecules. For example.g-like domains occur in several different types of receptors (such as various T-cell antigen receptors).everal cell adhesion molecules.HC class I and II antigens.s well as the hemolymph protein hemolin.nd the muscle proteins titin.elokin and twitchin.
  IPR013783:Immunoglobulin-like fold
IPR013783:Ig-like_fold 
Evalue:0 
Location:27-118IPR013783:Ig-like_fold 
Evalue:0 
Location:122-191
SequencesProtein: Q6PI73_HUMAN (193 aa)
mRNA: BC041708
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentK06512
  Level 3 annotation:
    leukocyte immunoglobulin-like receptor
  Level 2 annotation:
    CD molecules
    B cell receptor signaling pathway
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 201 residues, 59432280-59432881Exon2: 44 residues, 59434173-59434301Exon3: 91 residues, 59434509-59434777Exon4: 19 residues, 59435588-59435639Exon5: 103 residues, 59435961-59436264Exon6: 101 residues, 59436518-59436815Exon7: 74 residues, 59437349-59437566Exon8: 97 residues, 59437713-59437998Exon9: 14 residues, 59438182-59438218Exon10: 19 residues, 59438378-59438429Exon11: 2 residues, -Jump to Q6PI73_HUMAN  
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Loci Cluster (Details)Loci: 3136 59107882-59138080 ~-30K 19560(CACNG7)(+)Loci: 3137 59158105-59177951 ~-20K 19561(CACNG8)(+)Loci: 3138 59187353-59207730 ~-20K 19562(CACNG6)(+)Loci: 4416 59432280-59438429 ~-6K 19590(-)Loci: 3135 59077278-59102713 ~-25K 19559(PRKCG)(+)Link out to UCSC