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1Q68DA4_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionHypothetical protein dkfzp781a1532.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005525 GTP binding (IEA)
0051020 GTPase binding (IEA)
0005085 guanyl-nucleotide exchange factor activity (IEA)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family represents a conserved region of approximately 200 residues within a number of eukaryotic dedicator of cytokinesis (DOCK) proteins. These proteins are potential guanine nucleotide exchange factors that activate some small GTPases.uch as Rac.y exchanging bound GDP for free GTP . DOCK proteins are required during several cellular processes.uch as cell motility and phagocytosis. For instance.OCK2 is specifically expressed in haemopoietic cells.nd plays a critical role in lymphocyte migration .
  IPR010703:Dedicator of cytokinesis
IPR010703:Ded_cyto 
Evalue:-98.6989669799805 
Location:966-1145
SequencesProtein: Q68DA4_HUMAN (1186 aa)
mRNA: NM_014689
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 250 residues, 225338051-225338798Exon2: 48 residues, 225343171-225343310Exon3: 35 residues, 225343505-225343606Exon4: 65 residues, 225346117-225346308Exon5: 72 residues, 225347865-225348076Exon6: 51 residues, 225351098-225351245Exon7: 40 residues, 225359982-225360096Exon8: 43 residues, 225360235-225360358Exon9: 37 residues, 225362024-225362131Exon10: 35 residues, 225365934-225366033Exon11: 21 residues, 225366360-225366418Exon12: 74 residues, 225367839-225368055Exon13: 39 residues, 225369276-225369387Exon14: 63 residues, 225369924-225370107Exon15: 48 residues, 225370792-225370930Exon16: 39 residues, 225373111-225373224Exon17: 43 residues, 225374876-225375001Exon18: 36 residues, 225377072-225377174Exon19: 18 residues, 225377754-225377802Exon20: 24 residues, 225378018-225378085Exon21: 40 residues, 225378166-225378281Exon22: 42 residues, 225378368-225378490Exon23: 39 residues, 225379086-225379198Exon24: 41 residues, 225380628-225380745Exon25: 60 residues, 225380871-225381047Exon26: 17 residues, 225387280-225387325Exon27: 34 residues, 225389577-225389674Exon28: 30 residues, 225392406-225392490Exon29: 51 residues, 225396461-225396608Exon30: 26 residues, 225403501-225403573Exon31: 17 residues, 225407110-225407157Exon32: 2 residues, -Jump to Q68DA4_HUMAN  
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