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1Q5VWX9_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionPeroxisomal n1-acetyl-spermine/spermidine oxidase (pao).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0016491 oxidoreductase activity (IEA)
0006118 electron transport (IEA)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains assigned to SynO:
This entry consists of various amine oxidases.ncluding maize polyamine oxidase (PAO) .-amino acid oxidases (LAO) and various flavin containing monoamine oxidases (MAO). The aligned region includes the flavin binding site of theseenzymes.In vertebrates MAO plays an important role in regulating the intracellular levels of amines via their oxidation; these include various neurotransmitters.eurotoxins and trace amines . In lower eukaryotessuch as aspergillus and in bacteria the main role of amine oxidases is to provide a source of ammonium .PAOs in plants.acteria and protozoa oxidise spermidine and spermine to an aminobutyral.iaminopropane and hydrogen peroxide and are involved in the catabolism of polyamines .Other members of this family include tryptophan 2-monooxygenase.utrescine oxidase.orticosteroid binding proteins and antibacterial glycoproteins.
  IPR002937:Amine oxidase
IPR002937:Amino_oxidase 
Evalue:-8.82390880584717 
Location:81-161
SequencesProtein: Q5VWX9_HUMAN (196 aa)
mRNA: AY541513 AY541519 AY541520 NM_152911 NM_207125 NM_207128
Local Annotation
Synapse Ontology
?
sdb:0328 transmitters release and endocytosis  (Evidence:domains)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 88 residues, 135042730-135042991Exon2: 164 residues, 135043492-135043979Exon3: 68 residues, 135044953-135045153Exon4: 86 residues, 135047453-135047706Exon5: 39 residues, 135052449-135052562Exon6: 54 residues, 135053083-135053241Exon7: 129 residues, 135054805-135055187Exon8: 2 residues, -Jump to Q5VWX9_HUMANExon1: 88 residues, 135042730-135042991Exon2: 164 residues, 135043492-135043979Exon3: 68 residues, 135044953-135045153Exon4: 86 residues, 135047453-135047706Exon5: 39 residues, 135052449-135052562Exon6: 129 residues, 135054805-135055187Exon7: 2 residues, -Jump to Q5VWX9_HUMANExon1: 88 residues, 135042730-135042991Exon2: 164 residues, 135043492-135043979Exon3: 68 residues, 135044953-135045153Exon4: 39 residues, 135052449-135052562Exon5: 54 residues, 135053083-135053241Exon6: 129 residues, 135054805-135055187Exon7: 2 residues, -Jump to Q5VWX9_HUMANExon1: 71 residues, 135042780-135042991Exon2: 164 residues, 135043492-135043979Exon3: 68 residues, 135044953-135045153Exon4: 8 residues, 135047453-135047473Exon5: 31 residues, 135047617-135047706Exon6: 39 residues, 135052449-135052562Exon7: 54 residues, 135053083-135053241Exon8: 106 residues, 135054805-135055118Exon9: 2 residues, -Jump to Q5VWX9_HUMANExon1: 72 residues, 135042780-135042993Exon2: 164 residues, 135043491-135043979Exon3: 68 residues, 135044953-135045153Exon4: 86 residues, 135047453-135047706Exon5: 39 residues, 135052449-135052562Exon6: 54 residues, 135053083-135053241Exon7: 106 residues, 135054805-135055118Exon8: 2 residues, -Jump to Q5VWX9_HUMANExon1: 71 residues, 135042780-135042991Exon2: 164 residues, 135043492-135043979Exon3: 68 residues, 135044953-135045153Exon4: 39 residues, 135052449-135052562Exon5: 54 residues, 135053083-135053241Exon6: 106 residues, 135054805-135055118Exon7: 2 residues, -Jump to Q5VWX9_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2641 135042730-135055187 ~-12K 6006(+)Loci: 3926 134988922-135000401 ~-11K 6002(DRD1IP)(-)Link out to UCSC