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1Q58AB0_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
NameN/A
DescriptionSkeletal muscle abundant protein 2.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Bromodomains are found in a variety of mammalian.nvertebrate and yeast DNA-binding proteins . Bromodomains can interact withacetylated lysine .In some proteins.he classical bromodomain has diverged to such an extent that parts of the region are either missing or contain an insertion (e.g..ammalian protein HRX.aenorhabditis elegans hypothetical protein ZK783.4.east protein YTA7). The bromodomain may occur as a single copy.r in duplicate. The precise function of the domain is unclear.ut it may be involved in protein-protein interactions and may play a role in assembly or activity of multi-component complexes involved in transcriptional activation .
  IPR001487:Bromodomain
IPR001487:BROMO 
Evalue:-39.1079053973095 
Location:677-785
SequencesProtein: Q58AB0_HUMAN (835 aa)
mRNA: BC008039 CR595657 NM_006696 NM_183359 X94234
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 8 residues, 137412871-137412892Exon2: 120 residues, 137520501-137520855Exon3: 37 residues, 137523656-137523761Exon4: 61 residues, 137524478-137524656Exon5: 25 residues, 137525383-137525452Exon6: 33 residues, 137525641-137525734Exon7: 73 residues, 137526717-137526932Exon8: 17 residues, 137527674-137527721Exon9: 33 residues, 137527907-137528001Exon10: 153 residues, 137528301-137528754Exon11: 95 residues, 137529415-137529696Exon12: 50 residues, 137531521-137531666Exon13: 75 residues, 137532057-137532276Exon14: 47 residues, 137532809-137532946Exon15: 23 residues, 137533932-137533997Exon16: 29 residues, 137534419-137534500Exon17: 43 residues, 137534625-137534748Exon18: 18 residues, 137534948-137534998Exon19: 25 residues, 137535652-137535722Exon20: 34 residues, 137541158-137541255Exon21: 2 residues, -Jump to Q58AB0_HUMANExon1: 133 residues, 137503358-137503754Exon2: 61 residues, 137504292-137504470Exon3: 25 residues, 137508764-137508833Exon4: 32 residues, 137509376-137509466Exon5: 54 residues, 137513227-137513385Exon6: 90 residues, 137514332-137514596Exon7: 95 residues, 137516069-137516348Exon8: 17 residues, 137523142-137523187Exon9: 37 residues, 137523656-137523761Exon10: 61 residues, 137524478-137524656Exon11: 25 residues, 137525383-137525452Exon12: 33 residues, 137525641-137525734Exon13: 73 residues, 137526717-137526932Exon14: 17 residues, 137527674-137527721Exon15: 33 residues, 137527907-137528001Exon16: 153 residues, 137528301-137528754Exon17: 95 residues, 137529415-137529696Exon18: 72 residues, 137530105-137530315Exon19: 50 residues, 137531521-137531666Exon20: 47 residues, 137532809-137532946Exon21: 23 residues, 137533932-137533997Exon22: 29 residues, 137534419-137534500Exon23: 43 residues, 137534625-137534748Exon24: 18 residues, 137534948-137534998Exon25: 25 residues, 137535652-137535722Exon26: 34 residues, 137541158-137541255Exon27: 26 residues, 137542183-137542257Exon28: 2 residues, -Jump to BRD8_HUMANExon1: 124 residues, 137520484-137520855Exon2: 17 residues, 137523142-137523187Exon3: 37 residues, 137523656-137523761Exon4: 61 residues, 137524478-137524656Exon5: 25 residues, 137525383-137525452Exon6: 33 residues, 137525641-137525734Exon7: 73 residues, 137526717-137526932Exon8: 17 residues, 137527674-137527721Exon9: 33 residues, 137527907-137528001Exon10: 153 residues, 137528301-137528754Exon11: 95 residues, 137529415-137529696Exon12: 72 residues, 137530105-137530315Exon13: 50 residues, 137531521-137531666Exon14: 75 residues, 137532057-137532276Exon15: 47 residues, 137532809-137532946Exon16: 23 residues, 137533932-137533997Exon17: 29 residues, 137534419-137534500Exon18: 43 residues, 137534625-137534748Exon19: 18 residues, 137534948-137534998Exon20: 25 residues, 137535652-137535722Exon21: 34 residues, 137541158-137541255Exon22: 7 residues, 137542183-137542199Exon23: 2 residues, -Jump to Q58AB0_HUMANExon1: 124 residues, 137520484-137520855Exon2: 17 residues, 137523142-137523187Exon3: 37 residues, 137523656-137523761Exon4: 61 residues, 137524478-137524656Exon5: 25 residues, 137525383-137525452Exon6: 33 residues, 137525641-137525734Exon7: 73 residues, 137526717-137526932Exon8: 17 residues, 137527674-137527721Exon9: 33 residues, 137527907-137528001Exon10: 153 residues, 137528301-137528754Exon11: 95 residues, 137529415-137529696Exon12: 72 residues, 137530105-137530315Exon13: 50 residues, 137531521-137531666Exon14: 75 residues, 137532057-137532276Exon15: 47 residues, 137532809-137532946Exon16: 23 residues, 137533932-137533997Exon17: 29 residues, 137534419-137534500Exon18: 43 residues, 137534625-137534748Exon19: 18 residues, 137534948-137534998Exon20: 25 residues, 137535652-137535722Exon21: 34 residues, 137541158-137541255Exon22: 26 residues, 137542183-137542257Exon23: 2 residues, -Jump to Q58AB0_HUMANExon1: 124 residues, 137520484-137520855Exon2: 37 residues, 137523656-137523761Exon3: 61 residues, 137524478-137524656Exon4: 25 residues, 137525383-137525452Exon5: 33 residues, 137525641-137525734Exon6: 73 residues, 137526717-137526932Exon7: 17 residues, 137527674-137527721Exon8: 33 residues, 137527907-137528001Exon9: 153 residues, 137528301-137528754Exon10: 95 residues, 137529415-137529696Exon11: 33 residues, 137530105-137530198Exon12: 50 residues, 137531521-137531666Exon13: 75 residues, 137532057-137532276Exon14: 47 residues, 137532809-137532946Exon15: 23 residues, 137533932-137533997Exon16: 27 residues, 137534424-137534500Exon17: 43 residues, 137534625-137534748Exon18: 18 residues, 137534948-137534998Exon19: 25 residues, 137535652-137535722Exon20: 34 residues, 137541158-137541255Exon21: 26 residues, 137542183-137542257Exon22: 2 residues, -Jump to Q58AB0_HUMANExon1: 115 residues, 137520513-137520855Exon2: 37 residues, 137523656-137523761Exon3: 61 residues, 137524478-137524656Exon4: 25 residues, 137525383-137525452Exon5: 33 residues, 137525641-137525734Exon6: 73 residues, 137526717-137526932Exon7: 17 residues, 137527674-137527721Exon8: 33 residues, 137527907-137528001Exon9: 153 residues, 137528301-137528754Exon10: 95 residues, 137529415-137529696Exon11: 50 residues, 137531521-137531666Exon12: 75 residues, 137532057-137532276Exon13: 44 residues, 137532809-137532937Exon14: 23 residues, 137533932-137533997Exon15: 29 residues, 137534419-137534500Exon16: 43 residues, 137534625-137534748Exon17: 18 residues, 137534948-137534998Exon18: 25 residues, 137535652-137535722Exon19: 34 residues, 137541158-137541255Exon20: 2 residues, -Jump to Q58AB0_HUMAN  
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Loci Cluster (Details)Loci: 4729 137412871-137542257 ~-129K 29467(-)Loci: 3480 137543247-137551259 ~-8K 29476(KIF20A)(+)Loci: 4730 137869686-137906817 ~-37K 29489(ETF1)(-)Loci: 4731 138236311-138238878 ~-3K 29494(LRRTM2)(-)Loci: 3479 137171360-137173313 ~-2K 29461(+)Link out to UCSC