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1Q496J9_HUMAN*   Trembl (?) | Description Local Annotation Link Reference
General Information
DescriptionSynaptic vesicle protein 2c.
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain ArchitectureN/A
SequencesProtein: Q496J9_HUMAN (727 aa)
mRNA: NM_014979
Local Annotation
Synapse Ontology
Penetrating at least one phospholipid bilayer of a synaptic vesicle membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
sdb:0078 integral to synaptic vesicle membrane proteins  (Evidence:keywords,domains)
the proteins transporting neurotransmitter, such as proton pump, neurotransmitter transporters.
sdb:0096 ion and neurotransmitter transport protein  (Evidence:keywords,domains)
proteins that help to traffick the vesicle, such as synaptobrevin/Vamp, synaptotagmin, Rab3-rabphilin complex.
sdb:0097 vesicle trafficking protein  (Evidence:keywords,domains)
Various stages of the synaptic vesicle cycle, including attachment, prefusion, triggering, recycling and reloading of the vesicles with transmitter.
sdb:0098 synaptic vesicle cycling  (Evidence:keywords,domains)
translating calcium signal into the corresponding biological event. Calcium may come from outside of the cell or subcelluar organelle to increase the cytosolic concentration.
sdb:0218 calcium sigal  (Evidence:keywords,domains)
calcium dependent short-term forms of presynaptic plasticity
sdb:0234 calcium dependent short-term forms of presynaptic plasticity  (Evidence:keywords,domains)
sdb:0293 extracelluar Ca influx  (Evidence:keywords,domains)
KO assignmentK06258
  Level 3 annotation:
    MFS transporter, VNT family, synaptic vesicle glycoprotein 2
  Level 2 annotation:
    Major facilitator superfamily (MFS)
    ECM-receptor interaction
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 12 residues, 75415060-75415093Exon2: 229 residues, 75463230-75463911Exon3: 62 residues, 75526499-75526680Exon4: 52 residues, 75541316-75541468Exon5: 46 residues, 75616742-75616876Exon6: 32 residues, 75617361-75617451Exon7: 39 residues, 75622801-75622912Exon8: 31 residues, 75623348-75623437Exon9: 57 residues, 75627358-75627523Exon10: 46 residues, 75630374-75630508Exon11: 70 residues, 75632309-75632513Exon12: 55 residues, 75632966-75633126Exon13: 78 residues, 75656944-75657172Exon14: 2 residues, -Jump to Q496J9_HUMAN  
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