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0PRA1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionPrenylated rab acceptor protein 1 (pra1 family protein 1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain ArchitectureN/A
SequencesProtein: PRA1_HUMAN (185 aa)
mRNA: NM_006423
Local Annotation
Synapse Ontology
Typical ecretory organelles, some 50 nm in diameter, of presynaptic nerve terminals; accumulate high concentrations of nonpeptide neurotransmitters and secrete these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
sdb:0094 typical synaptic vesicle  (Evidence:keywords)
Various stages of the synaptic vesicle cycle, including attachment, prefusion, triggering, recycling and reloading of the vesicles with transmitter.
sdb:0098 synaptic vesicle cycling  (Evidence:keywords)
priming for exocytosis prepares the calcium-dependent release and may involve partial fusion process. The vesicles are primed and become responsive to calcium.
sdb:0120 priming  (Evidence:keywords)
attachment of the vesicle filled with transmitters involves a specific interaction between the vesicle membrane and the presynaptic active zone.
sdb:0148 docking  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 84 residues, 47152677-47152926Exon2: 36 residues, 47153009-47153111Exon3: 34 residues, 47154277-47154375Exon4: 73 residues, 47154727-47154940Exon5: 29 residues, 47155228-47155311Exon6: 2 residues, -Jump to PRA1_HUMAN  
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Loci Cluster (Details)Loci: 4393 47162575-47190222 ~-28K 18940(ATP1A3)(-)Loci: 4394 47194312-47261797 ~-67K 18941(GRIK5)(-)Loci: 4395 47286962-47340851 ~-54K 18946(POU2F2)(-)Loci: 4396 47394591-47413653 ~-19K 18951(DEDD2)(-)Loci: 4392 47152677-47155311 ~-3K 18939(RABAC1)(-)Link out to UCSC