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0PLSB_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionGlycerol-3-phosphate acyltransferase, mitochondrial precursor (ec (gpat).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function . This family also includes tafazzin subfamily () .
  IPR002123:Phospholipid/glycerol acyltransferase
This group represents a glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase. Please see the following relevant references: .
  IPR012082:Glycerol-3-phosphate O-acyltransferase/dihydroxyacetone phosphate acyltransferase
SequencesProtein: PLSB_HUMAN (828 aa)
mRNA: NM_020918
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentK00629
  Level 3 annotation:
    glycerol-3-phosphate O-acyltransferase
  Level 2 annotation:
    Glycerolipid metabolism
    Glycerophospholipid metabolism
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 1268 residues, 113899611-113903414Exon2: 21 residues, 113904376-113904435Exon3: 65 residues, 113905611-113905801Exon4: 49 residues, 113906996-113907137Exon5: 28 residues, 113908063-113908141Exon6: 49 residues, 113909658-113909801Exon7: 90 residues, 113910351-113910616Exon8: 25 residues, 113911414-113911485Exon9: 40 residues, 113913448-113913564Exon10: 30 residues, 113914272-113914358Exon11: 40 residues, 113916149-113916263Exon12: 73 residues, 113918059-113918272Exon13: 35 residues, 113918600-113918700Exon14: 47 residues, 113921929-113922066Exon15: 34 residues, 113922717-113922814Exon16: 51 residues, 113923446-113923593Exon17: 40 residues, 113925347-113925461Exon18: 26 residues, 113927731-113927805Exon19: 43 residues, 113930220-113930343Exon20: 45 residues, 113931430-113931561Exon21: 34 residues, 113932541-113932639Exon22: 24 residues, 113933440-113933508Exon23: 2 residues, -Jump to PLSB_HUMAN  
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Loci Cluster (Details)Loci: 2634 114125012-114178127 ~-53K 5715(ACSL5)(+)Loci: 2635 114197005-114487522 ~-291K 5719(VTI1A)(+)Loci: 3921 113899611-113933508 ~-34K 5712(GPAM)(-)Link out to UCSC