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0PIGT_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NamePIGT
DescriptionGpi transamidase component pig-t precursor (phosphatidylinositol- glycan biosynthesis, class t protein).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
GPI (glycosyl phosphatidyl inositol) transamidase is a multiprotein complex. Gpi16.pi8 and Gaa1 for a sub-complex of the GPI transamidase. GPI transamidase adds glycosylphosphatidylinositols (GPIs) to newly synthesized proteins. Gpi16 is an essential N-glycosylated transmembrane glycoprotein. Gpi16 is largely found on the lumenal side of the ER. It has a single C-terminal transmembrane domain and a small C-terminal.ytosolic extension with an ER retrieval motif .
  IPR007245:Gpi16 subunit, GPI transamidase component
IPR007245:Gpi16 
Evalue:-1e+125 
Location:8-574
SequencesProtein: PIGT_HUMAN (578 aa)
mRNA: AY358588 NM_015937
Local Annotation
Synapse Ontology
the mechanism by which the restiong potential is held.
sdb:0288 maintain membrane potential  (Evidence:keywords)
KO assignmentK05292
  Level 3 annotation:
    phosphatidylinositol glycan, class T
  Level 2 annotation:
    Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 69 residues, 43478191-43478397Exon2: 61 residues, 43478570-43478748Exon3: 44 residues, 43480905-43481033Exon4: 35 residues, 43481348-43481449Exon5: 31 residues, 43481557-43481644Exon6: 31 residues, 43482189-43482277Exon7: 34 residues, 43482385-43482483Exon8: 57 residues, 43482581-43482747Exon9: 69 residues, 43483436-43483637Exon10: 57 residues, 43486269-43486435Exon11: 30 residues, 43486549-43486633Exon12: 224 residues, 43487627-43488295Exon13: 2 residues, -Jump to PIGT_HUMANExon1: 62 residues, 43478213-43478397Exon2: 61 residues, 43478570-43478748Exon3: 44 residues, 43480905-43481033Exon4: 35 residues, 43481348-43481449Exon5: 31 residues, 43481557-43481644Exon6: 31 residues, 43482189-43482277Exon7: 34 residues, 43482385-43482483Exon8: 57 residues, 43482581-43482747Exon9: 69 residues, 43483436-43483637Exon10: 57 residues, 43486269-43486435Exon11: 30 residues, 43486549-43486633Exon12: 225 residues, 43487627-43488296Exon13: 2 residues, -Jump to PIGT_HUMAN  
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Loci Cluster (Details)Loci: 3258 42947757-42970574 ~-23K 23159(YWHAB)(+)Loci: 3259 43028533-43142005 ~-113K 23166(STK4)(+)Loci: 4524 43154364-43163167 ~-9K 23170(KCNS1)(-)Loci: 3260 43478191-43488296 ~-10K 23191(PIGT)(+)Loci: 4523 42813862-42872326 ~-58K 23158(RIMS4)(-)Link out to UCSC