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0PAHX_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NamePHYH
DescriptionPhytanoyl-coa dioxygenase, peroxisomal precursor (ec 1.14.11.18) (phytanoyl-coa alpha-hydroxylase) (phyh) (phytanic acid oxidase).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005777 peroxisome (TAS)
0003824 catalytic activity (TAS)
0005489 electron transporter activity (TAS)
0006629 lipid metabolism (TAS)
0007399 neurogenesis (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family is made up of several eukaryotic phytanoyl-CoA dioxygenase (PhyH) proteins as well as a number of bacterial deoxygenases. PhyH is a peroxisomal enzyme catalysing the first step of phytanic acid alpha-oxidation. PhyH deficiency causes Refsums disease (RD) which is an inherited neurological syndrome biochemically characterised by the accumulation of phytanic acid in plasma and tissues .
  IPR008775:Phytanoyl-CoA dioxygenase
IPR008775:PhyH 
Evalue:-73.958610534668 
Location:59-277
SequencesProtein: PAHX_HUMAN (338 aa)
mRNA: NM_006214
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords)
KO assignmentK00477
  Level 3 annotation:
    phytanoyl-CoA hydroxylase
  Level 2 annotation:
    Other enzymes
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 187 residues, 13359802-13360360Exon2: 47 residues, 13362981-13363116Exon3: 52 residues, 13365695-13365845Exon4: 62 residues, 13370365-13370547Exon5: 29 residues, 13373836-13373918Exon6: 58 residues, 13376433-13376602Exon7: 39 residues, 13377501-13377612Exon8: 21 residues, 13380192-13380251Exon9: 56 residues, 13381973-13382136Exon10: 2 residues, -Jump to PAHX_HUMAN  
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