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0PAFA2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NamePAFAH2
DescriptionPlatelet-activating factor acetylhydrolase 2, cytoplasmic (ec 3.1.1.47) (serine dependent phospholipase a2) (hsd-pla2).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005543 phospholipid binding (TAS)
0006629 lipid metabolism (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Platelet-activating factor acetylhydrolase (PAF-AH) is a subfamily of phospholipase A2 responsible for inactivation of platelet-activating factor through cleavage of an acetyl group. Three known PAF-AHs are the brain heterotrimeric PAF-AH Ib.he extracellular.lasma PAF-AH (pPAF-AH).nd the intracellular PAF-AH isoform II (PAF-AH II).
  IPR005065:Platelet-activating factor acetylhydrolase, plasma/intracellular isoform II
IPR005065:PAF-AH_p_II 
Evalue:-258.886047363281 
Location:1-381
SequencesProtein: PAFA2_HUMAN (392 aa)
mRNA: NM_000437
Local Annotation
Synapse Ontology
Microglias, one kind of glias in CNS, are responsible for removing most of the waste and cellular debris from the CNS
sdb:0267 removing metabolic mass  (Evidence:keywords)
KO assignmentK01062
  Level 3 annotation:
    1-alkyl-2-acetylglycerophosphocholine esterase
  Level 2 annotation:
    Glycerophospholipid metabolism
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 421 residues, 26159901-26161161Exon2: 53 residues, 26171635-26171790Exon3: 59 residues, 26173557-26173728Exon4: 32 residues, 26175759-26175851Exon5: 40 residues, 26181441-26181555Exon6: 49 residues, 26183023-26183165Exon7: 25 residues, 26183537-26183606Exon8: 34 residues, 26187308-26187405Exon9: 53 residues, 26188525-26188679Exon10: 47 residues, 26189804-26189941Exon11: 46 residues, 26197102-26197235Exon12: 2 residues, -Jump to PAFA2_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 3784 26099194-26105231 ~-6K 763(STMN1)(-)Loci: 3785 26159901-26197235 ~-37K 764(PAFAH2)(-)Loci: 2492 25742752-25767962 ~-25K 748(LDLRAP1)(+)Link out to UCSC