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0NUKM_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameNDUFS7
DescriptionNadh-ubiquinone oxidoreductase 20 kda subunit, mitochondrial precursor (ec 1.6.5.3) (ec 1.6.99.3) (complex i-20kd) (ci-20kd) (psst subunit).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0016655 oxidoreductase activity, acting on NADH or ... (NAS)
0006120 mitochondrial electron transport, NADH to u... (NAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Respiratory-chain NADH dehydrogenase () (also known as complex I or NADH-ubiquinone oxidoreductase) is an oligomeric enzymatic complex located in the inner mitochondrial membrane which also seems to exist in the chloroplast and in cyanobacteria (as a NADH-plastoquinone oxidoreductase). Among the 25 to 30 polypeptide subunits of this bioenergetic enzyme complex there is one with a molecular weight of 20 kDa (in mammals) .hich is a component of the iron-sulphur (IP) fragment of the enzyme. It seems to bind a 4Fe-4S iron-sulphur cluster. The 20 kDa subunit has been found to be nuclear encoded.s a precursor form with a transit peptide in mammals.nd in Neurospora crassa. It is mitochondrial encoded in Paramecium (gene psbG) and chloroplast encoded in various higher plants (gene ndhK or psbG).
  IPR006137:NADH ubiquinone oxidoreductase, 20 kDa subunit
IPR006137:Oxidored_q6 
Evalue:-63.3665313720703 
Location:91-198
SequencesProtein: NUKM_HUMAN (213 aa)
mRNA: NM_024407
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentK03940
  Level 3 annotation:
    NADH dehydrogenase (ubiquinone) Fe-S protein 7
  Level 2 annotation:
    Oxidative phosphorylation
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 90 residues, 1334888-1335155Exon2: 14 residues, 1338809-1338846Exon3: 140 residues, 1339523-1339937Exon4: 100 residues, 1341869-1342164Exon5: 783 residues, 1344240-1346583Exon6: 2 residues, -Jump to Q6ZQU6_HUMANExon1: 13 residues, 1334905-1334941Exon2: 14 residues, 1338809-1338846Exon3: 25 residues, 1339523-1339592Exon4: 37 residues, 1339831-1339937Exon5: 62 residues, 1341869-1342049Exon6: 17 residues, 1342117-1342164Exon7: 31 residues, 1344240-1344329Exon8: 66 residues, 1346389-1346582Exon9: 2 residues, -Jump to NUKM_HUMAN  
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Loci Cluster (Details)Loci: 4349 568224-584530 ~-16K 17494(POLRMT)(-)Loci: 3077 868357-872013 ~-4K 17519(GPR54)(+)Loci: 3078 951436-960723 ~-9K 17523(GRIN3B)(+)Loci: 3079 1192748-1195823 ~-3K 17537(ATP5D)(+)Loci: 3080 1334888-1346583 ~-12K 17550(+)Loci: 4350 1766247-1799450 ~-33K 17579(-)Loci: 4351 1988469-2002233 ~-14K 17594(MKNK2)(-)Loci: 4352 2051987-2102554 ~-51K 17601(AP3D1)(-)Loci: 3076 540892-568157 ~-27K 17493(HCN2)(+)Link out to UCSC