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0NT5M_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameNT5M
Description5'(3')-deoxyribonucleotidase, mitochondrial precursor (ec 3.1.3.-) (5',3'-nucleotidase, mitochondrial) (deoxy-5'-nucleotidase 2) (dnt-2).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005739 mitochondrion (TAS)
0008252 nucleotidase activity (TAS)
0006260 DNA replication (TAS)
0009223 pyrimidine deoxyribonucleotide catabolism (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family consists of several 5 nucleotidase.eoxy (Pyrimidine).nd cytosolic type C (NT5C) proteins. 5(3)-Deoxyribonucleotidase is a ubiquitous enzyme in mammalian cells whose physiological function is not known .
  IPR010708:5 nucleotidase, deoxy, cytosolic type C
IPR010708:NT5C 
Evalue:-174.88606262207 
Location:34-227
SequencesProtein: NT5M_HUMAN (228 aa)
mRNA: NM_020201
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentK01081
  Level 3 annotation:
    5'-nucleotidase
  Level 2 annotation:
    Purine metabolism
    Pyrimidine metabolism
    Nicotinate and nicotinamide metabolism
    CD molecules
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 151 residues, 17147404-17147856Exon2: 35 residues, 17150581-17150682Exon3: 22 residues, 17167223-17167284Exon4: 40 residues, 17188832-17188947Exon5: 287 residues, 17190843-17191700Exon6: 2 residues, -Jump to NT5M_HUMAN  
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Loci Cluster (Details)Loci: 2987 17147404-17191700 ~-44K 15242(NT5M)(+)Loci: 4270 17090865-17125316 ~-34K 15240(COPS3)(-)Link out to UCSC