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0NT5C_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameNT5C
Description5'(3')-deoxyribonucleotidase, cytosolic type (ec 3.1.3.-) (cytosolic 5',3'-pyrimidine nucleotidase) (deoxy-5'-nucleotidase 1) (dnt-1).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005634 nucleus (TAS)
0003714 transcription corepressor activity (TAS)
0003700 transcription factor activity (TAS)
0006357 regulation of transcription from RNA polyme... (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family consists of several 5 nucleotidase.eoxy (Pyrimidine).nd cytosolic type C (NT5C) proteins. 5(3)-Deoxyribonucleotidase is a ubiquitous enzyme in mammalian cells whose physiological function is not known .
  IPR010708:5 nucleotidase, deoxy, cytosolic type C
IPR010708:NT5C 
Evalue:-180.259643554687 
Location:3-196
SequencesProtein: NT5C_HUMAN (201 aa)
mRNA: NM_014595
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentK01081
  Level 3 annotation:
    5'-nucleotidase
  Level 2 annotation:
    Purine metabolism
    Pyrimidine metabolism
    Nicotinate and nicotinamide metabolism
    CD molecules
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 139 residues, 70637918-70638332Exon2: 40 residues, 70638442-70638557Exon3: 22 residues, 70638734-70638795Exon4: 35 residues, 70638870-70638971Exon5: 85 residues, 70639223-70639472Exon6: 2 residues, -Jump to NT5C_HUMAN  
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Loci Cluster (Details)Loci: 3038 70178864-70255068 ~-76K 16552(+)Loci: 3039 70256378-70277089 ~-21K 16559(SLC9A3R1)(+)Loci: 4310 70349762-70367602 ~-18K 16565(GRIN2C)(-)Loci: 4311 70370220-70380710 ~-10K 16567(FDXR)(-)Loci: 4312 70546549-70554669 ~-8K 16577(ATP5H)(-)Loci: 4313 70637918-70639472 ~-2K 16582(NT5C)(-)Loci: 4314 70744289-70769272 ~-25K 16589(GGA3)(-)Loci: 4315 70780668-70797109 ~-16K 16594(SLC25A19)(-)Loci: 4316 71265612-71272875 ~-7K 16620(GALK1)(-)Loci: 4317 71514521-71534972 ~-20K 16639(EVPL)(-)Loci: 4318 71546785-71580202 ~-33K 16642(SRP68)(-)Loci: 3040 71582486-71585168 ~-3K 16644(GALR2)(+)Loci: 3041 71586857-71590480 ~-4K 16645(+)Loci: 4319 71588681-71611451 ~-23K 16647(EXOC7)(-)Loci: 3037 69833964-69859062 ~-25K 16537(+)Link out to UCSC