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0NSG2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameNSG2
DescriptionNeuron specific protein family member 2 (protein p19) (hmp19).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains assigned to SynO:
This family consists of several D1 dopamine receptor-interacting (calcyon) proteins. D1/D5 dopamine receptors in the basal ganglia.ippocampus.nd cerebral cortex modulate motor.eward.nd cognitive behaviour. D1-like dopamine receptors likely modulate neocortical and hippocampal neuronal excitability and synaptic function via Ca2+ as well as cAMP-dependent signaling . Defective calcyon proteins have been implicated in both attention-deficit/hyperactivity disorder (ADHD) and schizophrenia.
  IPR009431:D1 dopamine receptor-interacting
IPR009431:Calcyon 
Evalue:-128.769546508789 
Location:1-170
SequencesProtein: NSG2_HUMAN (171 aa)
mRNA: NM_015980
Local Annotation
Synapse Ontology
translating calcium signal into the corresponding biological event. Calcium may come from outside of the cell or subcelluar organelle to increase the cytosolic concentration.
sdb:0218 calcium sigal  (Evidence:domains)
?
sdb:0219 GPCR mediated signaling  (Evidence:domains)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 42 residues, 173405329-173405452Exon2: 52 residues, 173406342-173406493Exon3: 30 residues, 173423840-173423924Exon4: 39 residues, 173463836-173463947Exon5: 623 residues, 173466922-173468787Exon6: 2 residues, -Jump to NSG2_HUMAN  
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