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0NSG1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameNSG1
DescriptionNeuron specific protein family member 1 (brain neuron cytoplasmic protein 1) (d4s234).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005737 cytoplasm (TAS)
0005634 nucleus (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains assigned to SynO:
This family consists of several D1 dopamine receptor-interacting (calcyon) proteins. D1/D5 dopamine receptors in the basal ganglia.ippocampus.nd cerebral cortex modulate motor.eward.nd cognitive behaviour. D1-like dopamine receptors likely modulate neocortical and hippocampal neuronal excitability and synaptic function via Ca2+ as well as cAMP-dependent signaling . Defective calcyon proteins have been implicated in both attention-deficit/hyperactivity disorder (ADHD) and schizophrenia.
  IPR009431:D1 dopamine receptor-interacting
IPR009431:Calcyon 
Evalue:-145.031524658203 
Location:1-185
SequencesProtein: NSG1_HUMAN (185 aa)
mRNA: NM_014392
Local Annotation
Synapse Ontology
translating calcium signal into the corresponding biological event. Calcium may come from outside of the cell or subcelluar organelle to increase the cytosolic concentration.
sdb:0218 calcium sigal  (Evidence:domains)
?
sdb:0219 GPCR mediated signaling  (Evidence:domains)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 50 residues, 4439652-4439801Exon2: 53 residues, 4440231-4440386Exon3: 41 residues, 4444102-4444219Exon4: 39 residues, 4462200-4462311Exon5: 233 residues, 4469862-4470555Exon6: 93 residues, 4471411-4471685Exon7: 2 residues, -Jump to NSG1_HUMAN  
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Loci Cluster (Details)Loci: 4662 4471598-4594676 ~-123K 27292(STX18)(-)Loci: 3404 4439652-4471685 ~-32K 27291(NSG1)(+)Link out to UCSC