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0NPFF_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameNPFF
DescriptionFmrfamide-related peptides precursor .
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005625 soluble fraction (TAS)
0005102 receptor binding (TAS)
0007218 neuropeptide signaling pathway (TAS)
0007268 synaptic transmission (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains assigned to SynO:
Neuropeptide FF (together with neuropeptides AF and SF.hich are derivedfrom the same precursor) belongs to a family of neuropeptides containing an RF-amide motif at their C-termini . Neuropeptide FF is found at highconcentrations in the posterior pituitary.pinal cord.ypothalamus and medulla.nd is believed to be involved in pain modulation.pioid tolerance.ardiovascular regulation.emory and neuroendocrine regulation.
  IPR008065:FMRFamide-related peptide 2
IPR008065:FMRFamid_rel_pep 
Evalue:0 
Location:5-113
SequencesProtein: NPFF_HUMAN (113 aa)
mRNA: BC104234 NM_003717
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:domains)
focus on function of synapse, corresponding to the structure of synapse.
sdb:0003 physiology/function at synapse  (Evidence:domains)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 69 residues, 52186740-52186944Exon2: 42 residues, 52187071-52187193Exon3: 90 residues, 52187423-52187689Exon4: 2 residues, -Jump to NPFF_HUMANExon1: 69 residues, 52186740-52186944Exon2: 191 residues, 52187071-52187639Exon3: 2 residues, -Jump to NPFF_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2755 50587468-50601120 ~-14K 8882(ACVRL1)(+)Loci: 2756 50631752-50677126 ~-45K 8883(ACVR1B)(+)Loci: 2757 50687014-50695938 ~-9K 8886(GRASP)(+)Loci: 4034 50965965-50971566 ~-6K 8896(KRTHB1)(-)Loci: 2758 50981917-50988684 ~-7K 8897(KRTHB6)(+)Loci: 4035 50994358-51001438 ~-7K 8898(KRTHB3)(-)Loci: 4036 51040058-51047576 ~-8K 8899(KRTHB5)(-)Loci: 4037 51057862-51065684 ~-8K 8900(KRTHB4)(-)Loci: 4038 51104120-51114373 ~-10K 8902(-)Loci: 4039 51148861-51153824 ~-5K 8903(KRT6D)(-)Loci: 4040 51167243-51173287 ~-6K 8904(KRT6A)(-)Loci: 4041 51194627-51200510 ~-6K 8905(KRT5)(-)Loci: 4042 51265639-51281559 ~-16K 8909(-)Loci: 4043 51448205-51457372 ~-9K 8917(KRT2P)(-)Loci: 4044 51486600-51494602 ~-8K 8920(KRT4)(-)Loci: 4045 51577237-51585127 ~-8K 8924(KRT8)(-)Loci: 2759 51629109-51632951 ~-4K 8926(KRT18)(+)Loci: 2761 51948817-51973697 ~-25K 8948(ESPL1)(+)Loci: 4046 52160546-52179538 ~-19K 8970(MAP3K12)(-)Loci: 4047 52186740-52187689 ~-1K 8973(NPFF)(-)Loci: 4048 52345211-52356779 ~-12K 8978(ATP5G2)(-)Loci: 2754 50271286-50488365 ~-217K 8878(SCN8A)(+)Link out to UCSC