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0N4BP2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameN4BP2
DescriptionNedd4-binding protein 2 (ec 3.-.-.-) (n4bp2) (bcl-3 binding protein).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family includes the Smr (Small MutS Related) proteins.nd the C-terminal region of the MutS2 protein. It has been suggested that this domain interacts with the MutS1 () protein in the case of Smr proteins and with the N-terminal MutS related region of MutS2.
  IPR002625:Smr protein/MutS2 C-terminal
This domain is almost always found adjacent to .
  IPR013899:Domain of unknown function DUF1771
UBA domains are a commonly occurring sequence motif of approximately 45 amino acid residues that are found in diverse proteins involved in the ubiquitin/proteasome pathway.NA excision-repair.nd cell signalling via protein kinases . HHR23A.he human homologue of yeast Rad23A is a nucleotide excision-repair protein that contains both an internal and a C-terminal UBA domain. The fold of the UBA domain consists of a compact three-helical bundle with a right-handed twist.nd have a conserved hydrophobic surface patch for protein-protein interactions. UBA-like domains can be found in other proteins as well.uch as the TS-N domain in the elongation factor Ts (EF-Ts).hich catalyses the recycling of the GTPase EF-Tu required for the binding of aminoacyl-tRNA top the ribosomal A site ; and the C-terminal domain of TAP/NXF1.hich functions in nuclear export through the interaction of its UBA-like domain with FG nucleoporins .The SSF signature in this entry is currently under review. Please be aware that some of the protein hits may be false positives.
  IPR009060:UBA-like
IPR002625:Smr 
Evalue:-29.1674919128418 
Location:1691-1770IPR013899:DUF1771 
Evalue:-25.4685211181641 
Location:1618-1683IPR009060:UBA_like 
Evalue:0 
Location:38-88
SequencesProtein: N4BP2_HUMAN (1770 aa)
mRNA: NM_018177
Local Annotation
Synapse Ontology
calcium-regulated transcription factor
sdb:0215 calcium-regulated transcription factor  (Evidence:keywords)
KO assignmentK01567
  Level 3 annotation:
    
  Level 2 annotation:
    Other enzymes
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 7 residues, 39751548-39751566Exon2: 116 residues, 39775241-39775584Exon3: 383 residues, 39780089-39781233Exon4: 43 residues, 39784914-39785039Exon5: 31 residues, 39790098-39790187Exon6: 27 residues, 39791446-39791523Exon7: 54 residues, 39795883-39796039Exon8: 794 residues, 39797946-39800324Exon9: 30 residues, 39801141-39801227Exon10: 17 residues, 39802174-39802220Exon11: 67 residues, 39804148-39804345Exon12: 41 residues, 39809815-39809934Exon13: 48 residues, 39814958-39815097Exon14: 65 residues, 39820687-39820876Exon15: 58 residues, 39822646-39822815Exon16: 43 residues, 39830794-39830918Exon17: 404 residues, 39832206-39833412Exon18: 2 residues, -Jump to N4BP2_HUMAN  
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Loci Cluster (Details)Loci: 3411 40032225-40051730 ~-20K 27493(CHRNA9)(+)Loci: 3410 39751548-39833412 ~-82K 27491(N4BP2)(+)Link out to UCSC