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0MTCH2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionMitochondrial carrier homolog 2 (met-induced mitochondrial protein).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
A variety of substrate carrier proteins that are involved in energy transfer are found in the inner mitochondrial membrane or integral to the membrane of other eukaryotic organelles such as the peroxisome . Such proteins include: ADP.TP carrier protein (ADP/ATP translocase); 2-oxoglutarate/malate carrier protein; phosphate carrier protein; tricarboxylate transport protein (or citrate transport protein); Graves disease carrier protein; yeast mitochondrial proteins MRS3 and MRS4; yeast mitochondrial FAD carrier protein; and many others. Structurally.hese proteins can consist of up to three tandem repeats of a domain of approximately 100 residues.ach domain containing two transmembrane regions.
  IPR001993:Mitochondrial substrate carrier
SequencesProtein: MTCH2_HUMAN (303 aa)
mRNA: NM_014342
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 535 residues, 47595443-47597047Exon2: 27 residues, 47600828-47600904Exon3: 24 residues, 47603801-47603869Exon4: 18 residues, 47605207-47605255Exon5: 33 residues, 47607080-47607174Exon6: 22 residues, 47608682-47608742Exon7: 19 residues, 47609163-47609215Exon8: 21 residues, 47609781-47609839Exon9: 23 residues, 47612799-47612862Exon10: 11 residues, 47613672-47613699Exon11: 37 residues, 47616826-47616933Exon12: 30 residues, 47617094-47617179Exon13: 46 residues, 47620506-47620640Exon14: 2 residues, -Jump to MTCH2_HUMAN  
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Loci Cluster (Details)Loci: 3949 47415890-47427306 ~-11K 6678(RAPSN)(-)Loci: 2664 47557207-47562689 ~-5K 6687(NDUFS3)(+)Loci: 3950 47595443-47620640 ~-25K 6689(MTCH2)(-)Loci: 3948 47155660-47164534 ~-9K 6654(PACSIN3)(-)Link out to UCSC