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0MPU1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameMPDU1
DescriptionMannose-p-dolichol utilization defect 1 protein (suppressor of lec15 and lec35 glycosylation mutation homolog) (sl15).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GON/A
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This repeated motif of unknown function has been found between the transmembrane helices of cystinosin.eastERS1 and mannose-P-dolichol utilization defect 1. The positioning of this repeat suggests that it may beassociated with the glycosylation machinery.
  IPR006603:Cystinosin/ERS1p repeat
Most of the members of this family are integral membrane lysosomal proteins and they are thought to transport cystines out of lysosomes.
  IPR005282:Lysosomal cystine transporter
IPR006603:PQ-loop 
Evalue:-22.508638381958 
Location:39-105IPR006603:CTNS 
Evalue:-2.88605664769316 
Location:167-198
SequencesProtein: MPU1_HUMAN (247 aa)
mRNA: NM_004870
Local Annotation
Synapse Ontology
the mechanism by which the restiong potential is held.
sdb:0288 maintain membrane potential  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 40 residues, 7427889-7428007Exon2: 24 residues, 7429773-7429839Exon3: 46 residues, 7429987-7430120Exon4: 30 residues, 7430733-7430819Exon5: 41 residues, 7430940-7431059Exon6: 39 residues, 7431202-7431313Exon7: 255 residues, 7431467-7432228Exon8: 2 residues, -Jump to MPU1_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 4258 6644024-6675784 ~-32K 14997(TEKT1)(-)Loci: 4259 7033935-7063745 ~-30K 15014(DLG4)(-)Loci: 2974 7063876-7069308 ~-5K 15016(ACADVL)(+)Loci: 4260 7084462-7086477 ~-2K 15021(GABARAP)(-)Loci: 2975 7252225-7263903 ~-12K 15047(NLGN2)(+)Loci: 2976 7289129-7301655 ~-13K 15051(CHRNB1)(+)Loci: 2977 7427889-7432228 ~-4K 15066(MPDU1)(+)Loci: 2978 7474184-7477419 ~-3K 15071(SHBG)(+)Loci: 4261 7512446-7531642 ~-19K 15074(TP53)(-)Loci: 4262 7774391-7775983 ~-2K 15094(TRAPPC1)(-)Loci: 2979 7846716-7864382 ~-18K 15097(GUCY2D)(+)Loci: 4263 8004447-8006987 ~-3K 15108(VAMP2)(-)Loci: 2980 8093361-8114528 ~-21K 15119(PFAS)(+)Loci: 2981 8279988-8330396 ~-50K 15135(+)Loci: 2973 6620295-6631688 ~-11K 14996(FBXO39)(+)Link out to UCSC