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0MLP3B_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionMicrotubule-associated proteins 1a/1b light chain 3b precursor (map1a/map1b lc3 b) (map1a/1b light chain 3 b) (map1 light chain 3- like protein 2) (autophagy-related protein lc3 b) (autophagy-related ubiquitin-like modifier lc3 b).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005515 protein binding (IPI)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Light chain 3 (LC3) may function primarily as a MAP1A and MAP1B subunit and its expression may regulate the microtubule binding activity of of the neuronal microtubule-associated proteins (MAPs).AP1A and MAP1B . Related proteins that belong to this group include the human ganglioside expression factor and a symbiosis-related fungal protein.
  IPR004241:Light chain 3 (LC3)
SequencesProtein: MLP3B_HUMAN (124 aa)
mRNA: NM_022818
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 86 residues, 85983319-85983574Exon2: 20 residues, 85989921-85989977Exon3: 37 residues, 85993281-85993388Exon4: 619 residues, 85994029-85995880Exon5: 2 residues, -Jump to MLP3B_HUMAN  
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