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0MLP3A_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
DescriptionMicrotubule-associated proteins 1a/1b light chain 3a precursor (map1a/map1b lc3 a) (map1a/1b light chain 3 a) (map1 light chain 3- like protein 1) (microtubule-associated protein 1 light chain 3 alpha) (autophagy-related protein lc3 a) (autophagy-related ubiquitin-like modifier lc3 a).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Light chain 3 (LC3) may function primarily as a MAP1A and MAP1B subunit and its expression may regulate the microtubule binding activity of of the neuronal microtubule-associated proteins (MAPs).AP1A and MAP1B . Related proteins that belong to this group include the human ganglioside expression factor and a symbiosis-related fungal protein.
  IPR004241:Light chain 3 (LC3)
SequencesProtein: MLP3A_HUMAN (121 aa)
mRNA: NM_032514
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 65 residues, 32610179-32610373Exon2: 20 residues, 32610672-32610728Exon3: 37 residues, 32610811-32610918Exon4: 205 residues, 32611200-32611810Exon5: 2 residues, -Jump to MLP3A_HUMAN  
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Loci Cluster (Details)Loci: 3249 32610179-32611810 ~-2K 22943(MAP1LC3A)(+)Loci: 4518 32766239-32877094 ~-111K 22948(NCOA6)(-)Loci: 3250 32928035-32979424 ~-51K 22955(ACSS2)(+)Loci: 3248 32567864-32592422 ~-25K 22941(DNCL2A)(+)Link out to UCSC