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0MGST1_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameMGST1
DescriptionMicrosomal glutathione s-transferase 1 (ec 2.5.1.18) (microsomal gst- 1) (microsomal gst-i).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0004364 glutathione transferase activity (TAS)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
This family describes a widespread superfamily of membrane-associated proteins withhighly divergent functions in eicosanoid and glutathione metabolism (MAPEG). Included arethe 5-lipoxygenase activating protein (gene FLAP) that seems to be required for the activation of 5-lipoxygenase.eukotriene C4 synthase () that catalyzes the production of LTC4 from LTA4and microsomal glutathione S-transferase II () (GST-II) that also produces LTC4 from LTA4.
  IPR001129:Membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG)
IPR001129:MAPEG 
Evalue:-21.236572265625 
Location:9-155
SequencesProtein: MGST1_HUMAN (155 aa)
mRNA: NM_145791
Local Annotation
Synapse Ontology
mitochondria are frequently observed in the vicinity of the synaptic vesicle clusters, in agreement with the ATP requirement of several steps of the vesicle cycle.
sdb:0118 mitochondria  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 41 residues, 16391978-16392099Exon2: 51 residues, 16398431-16398579Exon3: 33 residues, 16401805-16401900Exon4: 207 residues, 16407995-16408610Exon5: 2 residues, -Jump to MGST1_HUMAN  
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