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0MAP1B_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameMAP1B
DescriptionMicrotubule-associated protein 1b (map 1b) .
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005875 microtubule associated complex (TAS)
0005198 structural molecule activity (NAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
In MAP1B the basic region containing the KKEE and KKEVI motifs is responsible for the interaction between MAP1B and microtubules in vivo. This region bears no sequence relationship to the microtubule binding domains of kinesin.AP2.r tau .Neuraxin is a putative structural protein of the rat central nervous system that is immunologically related to microtubule-associated protein 5 (MAP5). Neuraxin may be implicated in neuronal membrane-microtubule interactions . Both proteins contain a region that consists of 12 tandemrepeats of a 17 residues motif.
  IPR000102:Neuraxin/MAP1B repeat
IPR000102:MAP1B_neuraxin 
Evalue:-6.49485015869141 
Location:1929-1945IPR000102:MAP1B_neuraxin 
Evalue:-6.09690999984741 
Location:1895-1911IPR000102:MAP1B_neuraxin 
Evalue:-5.88605642318726 
Location:2048-2064IPR000102:MAP1B_neuraxin 
Evalue:-5.74472761154175 
Location:2031-2047IPR000102:MAP1B_neuraxin 
Evalue:-5.69896984100342 
Location:1963-1979IPR000102:MAP1B_neuraxin 
Evalue:-4.408935546875 
Location:1878-1894IPR000102:MAP1B_neuraxin 
Evalue:-4.30980396270752 
Location:1946-1962IPR000102:MAP1B_neuraxin 
Evalue:-4.22914791107178 
Location:1997-2013IPR000102:MAP1B_neuraxin 
Evalue:-4.09690999984741 
Location:1912-1928IPR000102:MAP1B_neuraxin 
Evalue:-2.74472761154175 
Location:2014-2030
SequencesProtein: MAP1B_HUMAN (2468 aa)
mRNA: NM_005909
Local Annotation
Synapse Ontology
microtubules of the presynaptic compartment function as the tracks for the intense traffic of organelles from cell body to axon terminals and vice versa. It is generally excluded from the presynaptic vesicle cluster.Microtubules do not directly regulate synapse morphology or function
sdb:0087 microtubules  (Evidence:keywords)
the plasma membrane of the postsynaptic neuron. It apposes with presynaptic actiove zone.
sdb:0108 postsynaptic plasma membrane  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 137 residues, 71438890-71439298Exon2: 36 residues, 71447280-71447382Exon3: 29 residues, 71515325-71515408Exon4: 49 residues, 71518196-71518337Exon5: 2169 residues, 71525448-71531950Exon6: 81 residues, 71535145-71535384Exon7: 649 residues, 71536666-71538608Exon8: 2 residues, -Jump to MAP1B_HUMAN  
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Loci Cluster (Details)Loci: 3464 71050749-71052628 ~-2K 28983(CART)(+)Loci: 3465 71438890-71538608 ~-100K 28984(MAP1B)(+)Loci: 4717 71551111-71651809 ~-101K 28987(MRPS27)(-)Loci: 3463 70918909-70988981 ~-70K 28982(MCCC2)(+)Link out to UCSC