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0IP3KB_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameITPKB
DescriptionInositol-trisphosphate 3-kinase b (ec 2.7.1.127) (inositol 1,4,5- trisphosphate 3-kinase b) (ip3k b) (ip3 3-kinase b) (ip3k-b).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0008440 inositol trisphosphate 3-kinase activity (TAS)
0007165 signal transduction (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
ArgRIII has been demonstrated to be an inositol polyphosphate kinase which catalyses the reactionATP + 1D-myo-inositol 1..-trisphosphate = ADP + 1D-myo-inositol 1...-tetrakisphosphate.
  IPR005522:Inositol polyphosphate kinase
IPR005522:IPK 
Evalue:-169.22184753418 
Location:652-937
SequencesProtein: IP3KB_HUMAN (946 aa)
mRNA: NM_002221
Local Annotation
Synapse Ontology
transport of vesicles in the presynaptic neuron
sdb:0017 Mobilization: synapsins, CAM kinase I  (Evidence:keywords)
KO assignmentK00911
  Level 3 annotation:
    1D-myo-inositol-triphosphate 3-kinase
  Level 2 annotation:
    Inositol phosphate metabolism
    Calcium signaling pathway
    Phosphatidylinositol signaling system
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 1066 residues, 224886014-224889210Exon2: 26 residues, 224892002-224892074Exon3: 36 residues, 224893880-224893982Exon4: 70 residues, 224896244-224896449Exon5: 73 residues, 224901490-224901704Exon6: 35 residues, 224902995-224903095Exon7: 658 residues, 224989850-224991818Exon8: 2 residues, -Jump to IP3KB_HUMAN  
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