SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0HMOX2_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameHMOX2
DescriptionHeme oxygenase 2 (ec 1.14.99.3) (ho-2).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005489 electron transporter activity (TAS)
0004392 heme oxygenase (decyclizing) activity (TAS)

Warning: fopen(/home/kongl/syndb/www/temp/822507098.dot) [function.fopen]: failed to open stream: Permission denied in /home/kongl/syndb/www/sdb_pro.php on line 269

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 270

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 271

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 272

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 273

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 274

Warning: fwrite(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 299

Warning: fclose(): supplied argument is not a valid stream resource in /home/kongl/syndb/www/sdb_pro.php on line 300
schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains assigned to SynO:
Haem oxygenase () (HO) is the microsomal enzyme that.n animals.arries out the oxidation of haem.t cleaves the haem ring at the alpha-methene bridge to form biliverdin and carbon monoxide . Biliverdin is subsequently converted to bilirubin by biliverdin reductase. In mammals there are three isozymes of haem oxygenase: HO-1 to HO-3. The first two isozymes differ in their tissue expression and their inducibility: HO-1 is highly inducible by its substrate haem and by various non-haem substances.hile HO-2 is non-inducible. It has been suggested that HO-2 could be implicated in the production of carbon monoxide in the brain where it is said to act as a neurotransmitter. In the genome of the chloroplast of red algae as well as in cyanobacteria.here is a haem oxygenase (gene pbsA) that is the key enzyme in the synthesis of the chromophoric part of the photosynthetic antennae . A haem oxygenase is also present in the bacteria Corynebacterium diphtheriae (gene hmuO).here it is involved in the acquisition of iron from the host haem . There is.n the central section of these enzymes. well-conserved region centred on a histidine residue.
  IPR002051:Haem oxygenase
IPR002051:Heme_oxygenase 
Evalue:-123.585029602051 
Location:31-236
SequencesProtein: HMOX2_HUMAN (316 aa)
mRNA: NM_002134
Local Annotation
Synapse Ontology
introduce the substructure of the synapse and the location where the molecule can be seen. It will contain all the constructive special organelle and molecule we known.
sdb:0001 Structure/Biochemistry of synapse  (Evidence:keywords,domains)
?
sdb:0328 transmitters release and endocytosis  (Evidence:keywords,domains)
KO assignmentK00510
  Level 3 annotation:
    heme oxygenase
  Level 2 annotation:
    Porphyrin and chlorophyll metabolism
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 15 residues, 4466446-4466489Exon2: 44 residues, 4495485-4495612Exon3: 41 residues, 4496896-4497014Exon4: 166 residues, 4497714-4498206Exon5: 44 residues, 4499413-4499540Exon6: 241 residues, 4499630-4500348Exon7: 2 residues, -Jump to HMOX2_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 2921 4415882-4446774 ~-31K 13438(DNAJA3)(+)Loci: 2922 4466446-4500348 ~-34K 13441(HMOX2)(+)Loci: 4208 4872508-4927137 ~-55K 13462(PPL)(-)Loci: 4207 4247192-4262891 ~-16K 13431(TFAP4)(-)Link out to UCSC