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0HDAC5_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameHDAC5
DescriptionHistone deacetylase 5 (hd5) (antigen ny-co-9).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0005737 cytoplasm (TAS)
0000118 histone deacetylase complex (TAS)
0005634 nucleus (TAS)
0004407 histone deacetylase activity (TAS)
0016566 specific transcriptional repressor activity (TAS)
0008134 transcription factor binding (TAS)
0030183 B cell differentiation (TAS)
0006338 chromatin remodeling (TAS)
0006342 chromatin silencing (TAS)
0006954 inflammatory response (TAS)
0045843 negative regulation of myogenesis (TAS)
0000074 regulation of progression through cell cycle (TAS)
0006355 regulation of transcription, DNA-dependent (TAS)

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schematic display of those terms with internal associations, click the node and browse the corresponding GO term
Domain Architecture (Details)
InterPro domains unassigned to SynO:
Histones can be reversibly acetylated on several lysine residues.Regulation of transcription is caused in part by thismechanism. Histone deacetylases catalyse the removalof the acetyl group. Histone deacetylases.cetoin utilization proteins and acetylpolyamine amidohydrolases are all members of this ancient protein superfamily .
  IPR000286:Histone deacetylase superfamily
IPR000286:Hist_deacetyl 
Evalue:-107.677780151367 
Location:682-1028
SequencesProtein: HDAC5_HUMAN (1122 aa)
mRNA: NM_001015053 NM_005474
Local Annotation
Synapse Ontology
transport of vesicles in the presynaptic neuron
sdb:0017 Mobilization: synapsins, CAM kinase I  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 555 residues, 39509646-39511309Exon2: 57 residues, 39511393-39511559Exon3: 30 residues, 39511688-39511773Exon4: 46 residues, 39512037-39512171Exon5: 41 residues, 39513000-39513119Exon6: 34 residues, 39513294-39513392Exon7: 42 residues, 39513656-39513776Exon8: 31 residues, 39515478-39515566Exon9: 20 residues, 39515658-39515714Exon10: 38 residues, 39516438-39516546Exon11: 18 residues, 39516698-39516748Exon12: 42 residues, 39517448-39517569Exon13: 46 residues, 39517915-39518049Exon14: 57 residues, 39519465-39519631Exon15: 97 residues, 39520305-39520590Exon16: 72 residues, 39521280-39521492Exon17: 76 residues, 39524163-39524386Exon18: 46 residues, 39524593-39524725Exon19: 39 residues, 39525065-39525178Exon20: 51 residues, 39525274-39525421Exon21: 45 residues, 39525569-39525700Exon22: 40 residues, 39525985-39526100Exon23: 59 residues, 39526207-39526379Exon24: 88 residues, 39526468-39526728Exon25: 26 residues, 39543622-39543694Exon26: 72 residues, 39550387-39550598Exon27: 49 residues, 39556397-39556540Exon28: 2 residues, -Jump to HDAC5_HUMANExon1: 555 residues, 39509646-39511309Exon2: 57 residues, 39511393-39511559Exon3: 30 residues, 39511688-39511773Exon4: 46 residues, 39512037-39512171Exon5: 41 residues, 39513000-39513119Exon6: 34 residues, 39513294-39513392Exon7: 42 residues, 39513656-39513776Exon8: 31 residues, 39515478-39515566Exon9: 20 residues, 39515658-39515714Exon10: 38 residues, 39516438-39516546Exon11: 18 residues, 39516698-39516748Exon12: 42 residues, 39517448-39517569Exon13: 46 residues, 39517915-39518049Exon14: 57 residues, 39519465-39519631Exon15: 97 residues, 39520305-39520590Exon16: 72 residues, 39521280-39521492Exon17: 76 residues, 39524163-39524386Exon18: 46 residues, 39524593-39524725Exon19: 39 residues, 39525065-39525178Exon20: 51 residues, 39525274-39525421Exon21: 45 residues, 39525569-39525700Exon22: 40 residues, 39525985-39526100Exon23: 59 residues, 39526207-39526379Exon24: 88 residues, 39526468-39526728Exon25: 27 residues, 39543622-39543697Exon26: 72 residues, 39550387-39550598Exon27: 49 residues, 39556397-39556540Exon28: 2 residues, -Jump to HDAC5_HUMAN  
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Loci Cluster (Details)Loci: 4294 39509646-39556540 ~-47K 15975(HDAC5)(-)Loci: 4295 39682565-39700993 ~-18K 15992(SLC4A1)(-)Loci: 4296 39752520-39757666 ~-5K 15997(-)Loci: 3010 40098011-40104116 ~-6K 16007(+)Loci: 4297 40237112-40263147 ~-26K 16016(GJA7)(-)Loci: 4298 40338518-40348394 ~-10K 16022(GFAP)(-)Loci: 3009 39437557-39441961 ~-4K 15971(NAGS)(+)Link out to UCSC