SynDB Home Page
SynDB Home Page
Browse
Search
Download
Help
People
links

blue bulletSynDB protein details  


Parse error: syntax error, unexpected T_VARIABLE in /home/kongl/syndb/www/sdb_nats.php on line 52
0GPR62_HUMAN*   SwissProt (?) | Description Local Annotation Link Reference
General Information
NameGPR62
DescriptionProbable g-protein coupled receptor 62 (hgpcr8).
SpeciesHomo sapiens (NCBI taxonomy ID: 9606)
GO0016526 G-protein coupled receptor activity, unknow... (NAS)
Domain Architecture (Details)
InterPro domains unassigned to SynO:
G-protein-coupled receptors.PCRs.onstitute a vast protein family that encompasses a wide range of functions (including various autocrine.aracrine and endocrine processes). They show considerable diversity at the sequence level.n the basis of which they can be separated into distinct groups. We use the term clan to describe the GPCRs.s they embrace a group of families for which there are indications of evolutionary relationship.ut between which there is no statistically significant similarity in sequence . The currently known clan members include the rhodopsin-like GPCRs.he secretin-like GPCRs.he cAMP receptors.he fungal mating pheromone receptors.nd the metabotropic glutamate receptor family. There is a specialized database for GPCRs: http://www.gpcr.org/7tm/. The rhodopsin-like GPCRs themselves represent a widespread protein family that includes hormone.eurotransmitter and light receptors.ll of which transduce extracellular signals through interaction with guanine nucleotide-binding (G) proteins. Although their activating ligands vary widely in structure and character.he amino acid sequences of the receptors are very similar and are believed to adopt a common structural framework comprising 7transmembrane (TM) helices .
  IPR000276:Rhodopsin-like GPCR superfamily
IPR000276:7tm_1 
Evalue:-8.95860767364502 
Location:31-290IPR000276:G_PROTEIN_RECEP_F1_1 
Evalue:0 
Location:0-0
SequencesProtein: GPR62_HUMAN (368 aa)
mRNA: NM_080865
Local Annotation
Synapse Ontology
Calcium release from RyR (Ryanodine Receptor) in the SR (Sarcoplasmic Reticulum) is activated by the calcium induced-calcium-release
sdb:0325 RyR-CICR  (Evidence:keywords)
KO assignmentNot mapped to KEGG
Loci Structure (Details)Loci index, Chromosomal location, Length, Possible relational loci clusterExon1: 708 residues, 51964436-51966559Exon2: 2 residues, -Jump to GPR62_HUMAN  
Tune and view alternative isoforms
Loci Cluster (Details)Loci: 3356 51964436-51966559 ~-2K 25814(GPR62)(+)Loci: 3355 51718003-51727663 ~-10K 25807(GRM2)(+)Link out to UCSC